Durairaj Kalpna K, Devgan Lara, Lee Bs Alexandria, Khachatourian Bs Nooneh, Nguyen Bs Vivian, Issa Bs Thomas, Baker Omer
A Medical Corp, Pasadena, California.
PLLC, New York, New York.
Dermatol Surg. 2020 Oct;46 Suppl 1:S46-S53. doi: 10.1097/DSS.0000000000002598.
Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volume augmentation of other extremities. However, research detailing PLLA buttock injections is still lacking.
The purpose of this study is to determine the safety and efficacy of PLLA for buttock augmentation.
A clinical retrospective review of 60 patients (ages 23-54 years) were followed for 2 years by 2 investigators. Patients underwent 1 to 3 treatments, spaced 4 to 6 weeks apart, and received 2 to 12 vials per session (based on the patient budget). Pretreatment and post-treatment photographs were assessed by the primary and secondary investigator in blinded and double-blinded surveys, respectively. The Global Aesthetic Improvement Scale was used to quantify improvements in volume, skin texture, and cellulite dimpling.
Poly-L-lactic acid allows for visible volume amplification, improved skin texture, and softened cellulite dimpling in the buttocks when at least 20 vials are used.
Poly-L-lactic acid is safe and effective for overall aesthetic enhancement of the buttocks if used in adequate quantity (minimum 20 vials) for all women, independent of age or the number of sessions.
聚左旋乳酸(PLLA)是一种成熟的生物刺激剂,可诱导新胶原形成,用于改善容量缺失。尽管PLLA已获美国食品药品监督管理局(FDA)批准用于治疗中下面部皱纹,但作为一种非手术、微创的软组织容量增加方法,它在其他部位的应用越来越广泛。然而,关于PLLA臀部注射的详细研究仍然缺乏。
本研究旨在确定PLLA用于臀部增大的安全性和有效性。
2名研究者对60例年龄在23至54岁之间的患者进行了为期2年的临床回顾性研究。患者接受1至3次治疗,每次间隔4至6周,每次注射2至12瓶(根据患者预算)。治疗前和治疗后的照片分别由主要研究者和次要研究者在单盲和双盲调查中进行评估。使用全球美学改善量表来量化体积、皮肤质地和橘皮组织凹陷的改善情况。
当使用至少20瓶PLLA时,可使臀部体积明显增大,改善皮肤质地,减轻橘皮组织凹陷。
对于所有女性,无论年龄或治疗次数如何,若使用足够剂量(至少20瓶)的聚左旋乳酸,对臀部进行整体美学改善是安全有效的。