Biosignatures: The answer to Tuberculosis diagnosis in children?
作者信息
Goussard Pierre, Walzl Gerhard
机构信息
Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.
DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research and South African Medical Research Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
出版信息
EBioMedicine. 2020 Oct;60:102977. doi: 10.1016/j.ebiom.2020.102977. Epub 2020 Sep 22.
Abstract
摘要
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本文引用的文献
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Identification of eight-protein biosignature for diagnosis of tuberculosis.鉴定用于诊断结核病的八蛋白生物标志物。
Thorax. 2020 Jul;75(7):576-583. doi: 10.1136/thoraxjnl-2018-213021. Epub 2020 Mar 22.
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-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting.用于在结核病流行地区诊断儿童结核病的特异性细胞因子生物标志物。
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3
Multiplex analysis of plasma cytokines/chemokines showing different immune responses in active TB patients, latent TB infection and healthy participants.对血浆细胞因子/趋化因子进行多重分析，结果显示活动性肺结核患者、潜伏性结核感染患者和健康参与者存在不同的免疫反应。
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Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.七种血清蛋白生物标志物对有疑似结核病症状和体征的非洲初级保健诊所就诊者中活动性结核病的诊断性能。
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Diagnosis of childhood tuberculosis and host RNA expression in Africa.非洲儿童结核病的诊断和宿主 RNA 表达。
N Engl J Med. 2014 May 1;370(18):1712-1723. doi: 10.1056/NEJMoa1303657.
6
Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting.宿主标志物在 Quantiferon 上清液中对高负担环境中儿童结核病的诊断价值。
PLoS One. 2013 May 15;8(5):e64226. doi: 10.1371/journal.pone.0064226. Print 2013.
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