Department of Statistics and Operational Research, University of Valencia, Valencia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.
Department of Geography, University of Santiago de Compostela, Santiago de Compostela, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.
Environ Res. 2021 Jan;192:110191. doi: 10.1016/j.envres.2020.110191. Epub 2020 Sep 24.
Climate change is a severe public health challenge. Understanding to what extent fatal and non-fatal consequences of specific diseases are associated with temperature may help to improve the effectiveness of preventive public health efforts. This study examines the effects of temperature on deaths and hospital admissions by cardiovascular and respiratory diseases, empathizing the difference between mortality and morbidity.
Daily counts for mortality and hospital admissions by cardiovascular and respiratory diseases were collected for the 52 provincial capital cities in Spain, between 1990 and 2014. The association with temperature in each city was investigated by means of distributed lag non-linear models using quasi-Poisson regression. City-specific exposure-response curves were pooled by multivariate random-effects meta-analysis to obtain countrywide risk estimates of mortality and hospitalizations due to heat and cold, and attributable fractions were computed.
Heat and cold exposure were identified to be associated with increased risk of cardiovascular and respiratory mortality. Heat was not found to have an impact on hospital admissions. The estimated fraction of mortality attributable to cold was of greater magnitude in hospitalizations (17.5% for cardiovascular and 12.5% for respiratory diseases) compared to deaths (9% and 2.7%, respectively).
There were noteworthy differences between temperature-related mortality and hospital admissions regarding cardiovascular and respiratory diseases, hence reinforcing the convenience of cause-specific measures to prevent temperature-related deaths.
气候变化是一个严重的公共卫生挑战。了解特定疾病的致死和非致死后果与温度的关联程度,有助于提高预防公共卫生措施的有效性。本研究通过心血管和呼吸疾病的死亡率和住院率来研究温度的影响,强调了发病率和死亡率之间的差异。
1990 年至 2014 年期间,收集了西班牙 52 个省会城市的心血管和呼吸疾病的每日死亡率和住院率数据。在每个城市中,采用分布滞后非线性模型,通过拟泊松回归分析温度与疾病的关系。通过多元随机效应荟萃分析对城市特异性暴露-反应曲线进行了汇总,以获得因冷热导致的死亡率和住院率的全国风险估计值,并计算了归因分数。
热暴露和冷暴露与心血管和呼吸疾病的死亡率增加有关。但热暴露与住院治疗无关。与死亡相比,归因于寒冷的死亡率在住院治疗中占比更大(心血管疾病为 17.5%,呼吸疾病为 12.5%),而在死亡中占比较小(心血管疾病为 9%,呼吸疾病为 2.7%)。
在心血管和呼吸疾病方面,与温度相关的死亡率和住院率之间存在显著差异,因此有必要采取特定病因的措施来预防与温度相关的死亡。