Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ann Thorac Surg. 2021 May;111(5):1512-1518. doi: 10.1016/j.athoracsur.2020.07.031. Epub 2020 Sep 24.
The anomalous insertion of papillary muscle directly into the anterior mitral leaflet is a rare congenital anomaly concomitant with hypertrophic cardiomyopathy. We herein report our surgical technique, which is designed to relieve left ventricular obstruction and preserve the mitral valve and subvalvular apparatus.
Among 38 patients who underwent septal myectomy from 2007 to 2020, 4 had an anomalous mitral subvalvular apparatus with papillary muscle with direct insertion into the anterior mitral leaflets. In all cases, mitral valve repair was accomplished with excision and reconstruction of all anomalous papillary muscles, concomitant with septal myectomy. In another 34 patients, 20 cases needed mitral valve repair with regard to systolic anterior motion by hypertrophic cardiomyopathy. The comparison study was conducted between the anomalous papillary muscle group (group A) and the others (group B).
There was no early or late death in group A, and there were 3 early deaths and 2 late deaths in group B. The mean peak gradient in the left ventricle was significantly decreased in both groups. Mitral valve regurgitation grade was also significantly decreased from 3 to 0.5 without valve replacement in group A, and from 2 to 0.6 in group B. Six patients needed mitral valve replacement because of the thickness of anterior mitral leaflet in group B.
Hypertrophic obstructive cardiomyopathy associated with the anomalous insertion of papillary muscle can be successfully treated without mitral valve replacement. Excision and reconstruction with the anomalous papillary muscle seems to be a feasible operation to reduce mitral regurgitation and relieve outflow tract obstruction.
乳头肌直接插入前二尖瓣的异常附着是一种罕见的先天性异常,常伴有肥厚型心肌病。我们在此报告我们的手术技术,旨在缓解左心室阻塞并保留二尖瓣和瓣下装置。
在 2007 年至 2020 年间接受室间隔切除术的 38 名患者中,有 4 名患者存在异常二尖瓣瓣下装置伴乳头肌直接插入前二尖瓣叶。在所有病例中,均通过切除和重建所有异常乳头肌来完成二尖瓣修复,同时进行室间隔切除术。在另外 34 名患者中,20 例因肥厚型心肌病导致收缩期前向运动而需要二尖瓣修复。对异常乳头肌组(A 组)和其他患者(B 组)进行了比较研究。
A 组无早期或晚期死亡,B 组有 3 例早期死亡和 2 例晚期死亡。两组左心室的平均峰值梯度均显著降低。二尖瓣反流程度也显著降低,A 组从 3 级降至 0.5 级,无需瓣膜置换,B 组从 2 级降至 0.6 级。B 组中有 6 名患者因前二尖瓣叶增厚而需要二尖瓣置换。
肥厚型梗阻性心肌病伴乳头肌异常附着可成功治疗,无需二尖瓣置换。切除和重建异常乳头肌似乎是一种可行的手术,可以减少二尖瓣反流并缓解流出道阻塞。