Efficacy and safety of ofloxacin in elderly patients.

A total of 325 patients all older than 65 years (45 of more than 80 years of age) were treated with ofloxacin during phase II studies. The relative efficacy of ofloxacin in the comparative studies in the elderly patients was comparable to that in the younger patients. However cure rates in the elderly patients were generally lower than in the younger patients both for ofloxacin and other comparative treatments, probably reflecting a higher incidence of complicating factors. Ofloxacin was well tolerated in the elderly patients.