Bruch K, Blomer R
Int J Clin Pharmacol Res. 1987;7(3):195-8.
A total of 325 patients all older than 65 years (45 of more than 80 years of age) were treated with ofloxacin during phase II studies. The relative efficacy of ofloxacin in the comparative studies in the elderly patients was comparable to that in the younger patients. However cure rates in the elderly patients were generally lower than in the younger patients both for ofloxacin and other comparative treatments, probably reflecting a higher incidence of complicating factors. Ofloxacin was well tolerated in the elderly patients.
在II期研究中，共有325名年龄均超过65岁（其中45名年龄超过80岁）的患者接受了氧氟沙星治疗。在老年患者的对比研究中，氧氟沙星的相对疗效与年轻患者相当。然而，无论是氧氟沙星治疗组还是其他对比治疗组，老年患者的治愈率普遍低于年轻患者，这可能反映出复杂因素的发生率较高。老年患者对氧氟沙星耐受性良好。
