Chavanet P, Arnould S, Sarret Y, Caillot D, Solary E, Portier H
Pathol Biol (Paris). 1987 May;35(5):620-3.
Fourty-two patients with 44 infective sites were treated with ofloxacin alone (22) or associated with an other antibiotic (20). Thirty-five patients (83%) and 37 infective localisations (84%) were cured. The treatment efficacy was similar for ofloxacin alone or associated, and for treatments given with first or second intent. All non-documented infections were cured. Two of the 4 failures were pneumococcal. So, the non-documented infections, the genital and urinary tract infections, the pulmonary infections (second intent) and osteitis seem to be the best indications of ofloxacin therapy.
42例有44个感染部位的患者单独使用氧氟沙星治疗（22例）或与其他抗生素联合使用（20例）。35例患者（83%）和37个感染部位（84%）治愈。单独使用氧氟沙星或联合使用时治疗效果相似，首次治疗或再次治疗时的效果也相似。所有未记录的感染均治愈。4例治疗失败中有2例是肺炎球菌感染。因此，未记录的感染、生殖器和泌尿道感染、肺部感染（再次治疗）和骨炎似乎是氧氟沙星治疗的最佳适应证。
