埃塞俄比亚西北部贡德尔镇女童父母对人乳头瘤病毒疫苗的接受情况及相关因素
Acceptance of Human Papillomavirus Vaccination and Associated Factors Among Parents of Daughters in Gondar Town, Northwest Ethiopia.
作者信息
Alene Tsigereda, Atnafu Asmamaw, Mekonnen Zeleke Abebaw, Minyihun Amare
机构信息
University of Gondar Specialized Comprehensive Hospital, University of Gondar, Gondar, Ethiopia.
Department of Health System and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
出版信息
Cancer Manag Res. 2020 Sep 16;12:8519-8526. doi: 10.2147/CMAR.S275038. eCollection 2020.
BACKGROUND
Cervical cancer is one of the profound threats to women's lives and the fourth most common cancer among women. Ethiopia launched the human papilloma vaccination for the first time, with the support of the Global Alliance for Vaccine and Immunization (GAVI) in 2018. Therefore, the aim of this study was to assess the acceptability of the human papillomavirus vaccine and associated factors among parents of daughters in Gondar town, Northwest Ethiopia.
METHODS
A community-based cross-sectional study with a total sample of 946 study participants was conducted in Gondar town from April to May 2019. The study participants were selected using a multistage sampling technique from parents having a daughter of 9-17 years age. Data were collected using an interviewer-administered questionnaire. The data were entered into EpiData version 4.2 and exported to STATA version 14 for analysis. Variables having a p-value of <0.2 and <0.05 in the bivariable and multivariable logistic regression were considered as a statistically significant factor for the acceptance of HPV vaccination.
RESULTS
A total of 899 study participants with a response rate of 95% were included in the study. Among participants in this study, 81.3% with 95% CI (78.6, 83.7) accepted to vaccinate their daughters for HPV vaccination. The acceptance to vaccinate daughters for HPV vaccination was affected by being from the richest household [AOR= 3.44, 95% CI = (1.97, 6.01)], good knowledge about cervical cancer [AOR=5.49, 95% CI= (2.62, 11.52)], and positive attitude towards HPV vaccination [AOR=21.53, 95% CI= (11.60, 39.96)].
CONCLUSION
The study revealed that the acceptance to human papillomavirus vaccination is high and was significantly associated with the level of knowledge about cervical cancer, the attitude towards HPV vaccination, and the wealth status of the households. Therefore, community education on cervical cancer and its prevention is crucial to increase awareness and acceptance as well.
背景
宫颈癌是对女性生命的重大威胁之一，也是女性中第四大常见癌症。2018年，在全球疫苗免疫联盟（GAVI）的支持下，埃塞俄比亚首次推出了人乳头瘤病毒疫苗。因此，本研究的目的是评估埃塞俄比亚西北部贡德尔镇女儿的父母对人乳头瘤病毒疫苗的接受程度及相关因素。
方法
2019年4月至5月在贡德尔镇进行了一项基于社区的横断面研究，共946名研究参与者。采用多阶段抽样技术从有9至17岁女儿的父母中选取研究参与者。通过访谈式问卷收集数据。数据录入EpiData 4.2版本并导出到STATA 14版本进行分析。在双变量和多变量逻辑回归中p值<0.2和<0.05的变量被视为接受HPV疫苗接种的统计学显著因素。
结果
共有899名研究参与者纳入研究，回复率为95%。在本研究的参与者中，81.3%（95%可信区间为78.6%，83.7%）接受为女儿接种HPV疫苗。为女儿接种HPV疫苗的接受程度受到来自最富裕家庭的影响[AOR = 3.44，95%可信区间 =（1.97，6.01）]、对宫颈癌的良好认知[AOR = 5.49，95%可信区间 =（2.62，11.52）]以及对HPV疫苗接种的积极态度[AOR = 21.53，95%可信区间 =（11.60，39.96）]。
结论
该研究表明，人乳头瘤病毒疫苗接种的接受程度较高，并且与宫颈癌的知识水平、对HPV疫苗接种的态度以及家庭财富状况显著相关。因此，关于宫颈癌及其预防的社区教育对于提高认识和接受程度也至关重要。
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