Lim Hse Juinn
Department of General Surgery, Royal Gwent Hospital, Newport, UK.
Ann Med Surg (Lond). 2020 Sep 9;59:48-52. doi: 10.1016/j.amsu.2020.08.048. eCollection 2020 Nov.
A review of the management of splenic artery aneurysms (SAA). There is no general consensus as to when and what type of intervention should be chosen to treat SAAs. The aim of this study is to investigate the types of intervention for SAAs including complication, reintervention, rupture, mortality after intervention of SAA in a review.
A literature search was performed using "keywords" in Medline and Embase limited to publications from 2008 to 2018. 289 articles were identified during the initial literature search. 143 articles met the eligibility criteria. 83 articles were included in the quantitative synthesis. Descriptive analysis was performed.
576 patients were identified with 588 reported SAAs. The mean ± SD age was 52.6 ± 5.8 years (range 17-85). The mean ± SD size of SAA was 49.9 ± 13.2 mm (range 6-180). Types of intervention reported were endovascular treatment, open surgery, laparoscopic surgery and conservative management. Mortality rate in patients with endovascular treatment was 0.5% compared to 4.9% with open surgery. 3.4% of patients with conservative management were reported to have aneurysms that grew over time and 2.8% patients had further intervention. ANOVA test to compare mortality between open surgery, endovascular treatment and laparoscopic surgery showed there is no difference between mortality between the 3 different interventions as F (2.71) < F crit (3.02) (P = 0.07).
Endovascular treatment is now the first choice of treatment for SAA, but future studies are required to determine its long-term durability. By introducing a management pathway for SAA, we hope to see an improvement in managing patients. The management algorithm will require further validation through application with careful and complete follow-up of all cases to improve the pathway depending on patient outcome.
脾动脉瘤(SAA)治疗方法的综述。对于何时以及应选择何种类型的干预措施来治疗SAA,目前尚无普遍共识。本研究的目的是在一项综述中调查SAA的干预类型,包括并发症、再次干预、破裂以及SAA干预后的死亡率。
使用“关键词”在Medline和Embase中进行文献检索,检索范围限于2008年至2018年发表的文献。在初步文献检索中识别出289篇文章。143篇文章符合纳入标准。83篇文章纳入定量综合分析,并进行描述性分析。
共识别出576例患者,报告了588个SAA。平均年龄±标准差为52.6±5.8岁(范围17 - 85岁)。SAA的平均大小±标准差为49.9±13.2mm(范围6 - 180mm)。报告的干预类型包括血管内治疗、开放手术、腹腔镜手术和保守治疗。血管内治疗患者的死亡率为0.5%,而开放手术患者的死亡率为4.9%。据报道,3.4%接受保守治疗的患者动脉瘤随时间增大,2.8%的患者需要进一步干预。比较开放手术、血管内治疗和腹腔镜手术死亡率的方差分析显示F(2.71)<F临界值(3.02)(P = 0.07),这三种不同干预措施的死亡率之间无差异。
血管内治疗目前是SAA的首选治疗方法,但需要进一步研究以确定其长期耐久性。通过引入SAA的管理途径,我们希望看到患者管理方面的改善。管理算法需要通过对所有病例进行仔细和完整的随访应用来进一步验证,以根据患者结果改进该途径。