Abdelaleem Nermeen A, Mohamed Sherif A A, Abd ElHafeez Azza S, Bayoumi Hassan A
Department of Chest Diseases and Tuberculosis.
Department of Medical Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Multidiscip Respir Med. 2020 Aug 6;15(1):691. doi: 10.4081/mrm.2020.691. eCollection 2020 Jan 28.
There is no consensus on the most useful predictive indicator for weaning patients from mechanical ventilation (MV). We aimed to evaluate the utility of the modified Burns Wean Assessment Program (m-BWAP) in predicting the weaning success in patients with respiratory disorders admitted to the respiratory intensive care unit (RICU).
Patients with respiratory failure requiring MV for longer than 48 hours were included. They were weaned by pressure support ventilation and spontaneous breathing trails. Patients were divided into successful and unsuccessful weaning groups according to their outcomes.
A total of 91 patients were enrolled. The majority had chronic obstructive pulmonary diseases (COPD): 40%, overlap syndrome (24%), and obesity hypoventilation syndrome (OHS): 15%. The successful group had significantly higher m-BWAP scores than that in the unsuccessful group (median 65; range 35 to 80 vs. median 45; range 30 to 65; p=0.000), with area under the curve (AUC) of 0.854; 95% CI 0.766 to 0.919), p<0.001. At cut-off value of ≥55, the sensitivity and specificity of m-BWAP to predict successful weaning were 73.77% and 84.85%, respectively. The AUC for m-BWAP was significantly higher than that for rapid shallow breathing index (RSBI).
We conclude that m-BWAP scores represent a good predictor of weaning success among patients with chronic respiratory disorders in the RICU. The m-BWAP checklist has many factors that are closely related to the weaning outcomes of patients with chronic respiratory disorders. Further, large-scale, multicenter studies are warranted.
对于机械通气(MV)患者撤机最有用的预测指标尚无共识。我们旨在评估改良版伯恩斯撤机评估程序(m - BWAP)在预测入住呼吸重症监护病房(RICU)的呼吸系统疾病患者撤机成功方面的效用。
纳入需要MV超过48小时的呼吸衰竭患者。他们通过压力支持通气和自主呼吸试验进行撤机。根据结果将患者分为撤机成功组和撤机失败组。
共纳入91例患者。大多数患者患有慢性阻塞性肺疾病(COPD):40%,重叠综合征(24%),肥胖低通气综合征(OHS):15%。成功组的m - BWAP评分显著高于失败组(中位数65;范围35至80 vs.中位数45;范围30至65;p = 0.000),曲线下面积(AUC)为0.854;95%置信区间0.766至0.919),p < 0.001。在截断值≥55时,m - BWAP预测撤机成功的敏感性和特异性分别为73.77%和84.85%。m - BWAP的AUC显著高于快速浅呼吸指数(RSBI)。
我们得出结论,m - BWAP评分是RICU中慢性呼吸系统疾病患者撤机成功的良好预测指标。m - BWAP检查表中有许多与慢性呼吸系统疾病患者撤机结果密切相关的因素。此外,有必要进行大规模、多中心研究。