Hudson Don A
Division of Plastic and Reconstructive Surgery, UCT Private Academic Hospital, Cape Town, South Africa.
Plast Reconstr Surg Glob Open. 2020 Aug 20;8(8):e3050. doi: 10.1097/GOX.0000000000003050. eCollection 2020 Aug.
Surgical adjuncts should improve surgical outcomes but should not increase complications. Epinephrine reduces bleeding in breast reduction, but various doses and volumes have been used. The ideal dose of epinephrine is still debated. The aim of this study was to assess blood loss after infiltration of 1 L of tumescent fluid containing epinephrine at a concentration of 1 in 100,000 (1 in 10) and 1200 mg of lignocaine in patients undergoing bilateral breast reduction.
Thirty-three consecutive patients undergoing bilateral breast reduction were included in the study. Data captured included age, mass of tissue removed, volume of blood loss, and surgical complications, especially hematoma formation.
The mean age was 41 years (range, 17-74 years). The mean mass of tissue removed was 786 g (range, 307-1339 g). The mean total blood loss was 76 mL (range, 50-200 mL)-that is, 38 mL per side. One patient presented with a unilateral swelling and pain after 48 hours and underwent exploration. A venous pool of <100 mL of blood was evacuated. One patient suffered bilateral nipple loss of >50%, and another patient suffered loss of 30%. The mean follow-up is 9 months (range, 2-20).
One liter of Ringer's lactate containing epinephrine at a concentration of 1 in 10, when injected into the breasts (500 mL per breast) before breast reduction, results in a massive reduction in blood loss.
手术辅助手段应改善手术效果,但不应增加并发症。肾上腺素可减少缩乳术中的出血,但使用的剂量和体积各不相同。肾上腺素的理想剂量仍存在争议。本研究的目的是评估在接受双侧缩乳术的患者中,注射1升含有浓度为十万分之一(十分之一)的肾上腺素和1200毫克利多卡因的肿胀液后的失血量。
本研究纳入了33例连续接受双侧缩乳术的患者。收集的数据包括年龄、切除组织的质量、失血量和手术并发症,尤其是血肿形成情况。
平均年龄为41岁(范围17 - 74岁)。切除组织的平均质量为786克(范围307 - 1339克)。平均总失血量为76毫升(范围50 - 200毫升),即每侧38毫升。1例患者在48小时后出现单侧肿胀和疼痛,并接受了探查。抽出了一个小于100毫升的静脉血池。1例患者双侧乳头丢失超过50%,另1例患者乳头丢失30%。平均随访时间为9个月(范围2 - 20个月)。
在缩乳术前,将1升含有浓度为十分之一肾上腺素的乳酸林格液注入乳房(每侧乳房500毫升),可显著减少失血量。