Coventry, United Kingdom From the Department of Plastic Surgery, University Hospitals of Coventry and Warwickshire NHS Trust.
Plast Reconstr Surg. 2012 Oct;130(4):773-778. doi: 10.1097/PRS.0b013e318262f085.
Evidence of the benefit of dilute epinephrine infiltration before reduction mammaplasty is provided by several controlled trials. Despite variation in operative technique and data collection, a reduction in intraoperative blood loss has been shown. The aim of this review of the literature is to weigh the available evidence with respect to reducing blood loss during surgery and other outcome measures such as postoperative drainage.
Two researchers independently selected articles for review, and data were extracted from each primary article and used for statistical and descriptive comparisons.
A meta-analysis of operative blood loss showed a highly significant drop in operative blood loss in breasts infiltrated with epinephrine and a reduction in the need for blood transfusion. Operative time, postoperative drainage, and complications were not significantly affected by epinephrine infiltration.
The authors' recommendation would be for the use of dilute epinephrine infiltration before reduction mammaplasty.
多项对照试验为在缩乳术前浸润稀释肾上腺素可带来益处提供了证据。尽管手术技术和数据收集存在差异，但术中失血量已显示减少。本次文献回顾旨在权衡现有证据，以了解手术期间减少失血量和其他结果指标（如术后引流）的情况。
两名研究人员独立选择文章进行综述，并从每篇原始文章中提取数据，用于统计和描述性比较。
手术失血量的荟萃分析显示，浸润肾上腺素的乳房手术失血量显著下降，输血需求减少。肾上腺素浸润对手术时间、术后引流和并发症没有显著影响。
作者建议在缩乳术前使用稀释肾上腺素浸润。
