McLeod M E, Creighton R E
J Child Neurol. 1986 Jul;1(3):189-97. doi: 10.1177/088307388600100303.
Children with neurological and neuromuscular diseases often present anesthetic problems in the perioperative period. The anesthetic technique can play a significant role in altering the state of the brain during neurosurgical procedures through effects on the cerebral circulation and metabolism. Pre-existing neuromuscular disease may also have specific anesthetic implications such as cardiorespiratory involvement (eg, myotonia dystrophica), the potential for drug interactions (eg, myasthenia gravis) or abnormal responses to commonly used drugs (eg, malignant hyperthermia). In this review, the perioperative anesthetic considerations in a number of common neurological and neuromuscular conditions in the pediatric patient are discussed.
患有神经和神经肌肉疾病的儿童在围手术期常常会出现麻醉问题。在神经外科手术过程中，麻醉技术可通过影响脑循环和代谢，在改变大脑状态方面发挥重要作用。既往存在的神经肌肉疾病也可能有特定的麻醉影响，如心肺受累（如肌强直性营养不良）、药物相互作用的可能性（如重症肌无力）或对常用药物的异常反应（如恶性高热）。在本综述中，将讨论小儿患者一些常见神经和神经肌肉疾病的围手术期麻醉注意事项。
