Suppr超能文献

在马拉维识别具有相似社会行为特征的人群,以提供艾滋病干预措施:一项潜在类别分析。

Identifying groups of people with similar sociobehavioural characteristics in Malawi to inform HIV interventions: a latent class analysis.

机构信息

Institute of Global Health, University of Geneva, Geneva, Switzerland.

University of Dundee, Dundee, United Kingdom.

出版信息

J Int AIDS Soc. 2020 Sep;23(9):e25615. doi: 10.1002/jia2.25615.

Abstract

INTRODUCTION

Within many sub-Saharan African countries including Malawi, HIV prevalence varies widely between regions. This variability may be related to the distribution of population groups with specific sociobehavioural characteristics that influence the transmission of HIV and the uptake of prevention. In this study, we intended to identify groups of people in Malawi with similar risk profiles.

METHODS

We used data from the Demographic and Health Survey in Malawi (2015 to 2016), and stratified the analysis by sex. We considered demographic, socio-behavioural and HIV-related variables. Using Latent Class Analysis (LCA), we identified groups of people sharing common sociobehavioural characteristics. The optimal number of classes (groups) was selected based on the Bayesian information criterion. We compared the proportions of individuals belonging to the different groups across the three regions and 28 districts of Malawi.

RESULTS

We found nine groups of women and six groups of men. Most women in the groups with highest risk of being HIV positive were living in female-headed households and were formerly married or in a union. Among men, older men had the highest risk of being HIV positive, followed by young (20 to 25) single men. Generally, low HIV testing uptake correlated with lower risk of having HIV. However, rural adolescent girls had a low probability of being tested (48.7%) despite a relatively high HIV prevalence. Urban districts and the Southern region had a higher percentage of high-prevalence and less tested groups of individuals than other areas.

CONCLUSIONS

LCA is an efficient method to find groups of people sharing common HIV risk profiles, identify particularly vulnerable sub-populations, and plan targeted interventions focusing on these groups. Tailored support, prevention and HIV testing programmes should focus particularly on female household heads, adolescent girls living in rural areas, older married men and young men who have never been married.

摘要

简介

在包括马拉维在内的许多撒哈拉以南非洲国家,艾滋病毒的流行率在各地区之间存在很大差异。这种变异性可能与具有特定社会行为特征的人群分布有关,这些特征会影响艾滋病毒的传播和预防措施的采用。在这项研究中,我们旨在确定马拉维具有相似风险特征的人群群体。

方法

我们使用了来自马拉维的人口与健康调查(2015 年至 2016 年)的数据,并按性别对分析进行分层。我们考虑了人口、社会行为和与艾滋病毒相关的变量。使用潜在类别分析(LCA),我们确定了具有共同社会行为特征的人群群体。基于贝叶斯信息准则,选择最佳的类别(群体)数量。我们比较了马拉维三个地区和 28 个区的不同群体中个体的比例。

结果

我们发现了 9 组女性和 6 组男性。处于艾滋病毒阳性最高风险的群体中的大多数女性生活在女性户主家庭中,曾经离婚或处于婚姻关系中。在男性中,年龄较大的男性感染艾滋病毒的风险最高,其次是年轻(20 至 25 岁)的单身男性。一般来说,艾滋病毒检测率低与艾滋病毒感染风险低相关。然而,农村地区的青春期女孩尽管艾滋病毒流行率相对较高,但接受检测的可能性较低(48.7%)。与其他地区相比,城市地区和南部地区的高流行率和低检测群体的比例更高。

结论

潜在类别分析是一种有效的方法,可以找到具有共同艾滋病毒风险特征的人群群体,确定特别脆弱的亚人群,并针对这些群体制定有针对性的干预措施。量身定制的支持、预防和艾滋病毒检测计划应特别关注女性户主、生活在农村地区的青春期女孩、已婚老年男性和从未结婚的年轻男性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8320/7521110/75516a4ce17a/JIA2-23-e25615-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验