1Mindong Hospital, Fuan, Ningde, China.
2The Affiliated Mindong Hospital of Fujian Medical University, Fuan, Ningde, China.
Acta Microbiol Immunol Hung. 2020 Sep 26;67(3):198-200. doi: 10.1556/030.2020.01207.
It may take time to obtain a vaccine for the current COVID-19, and the virus genome may keep an evolution and mutations, so a universal and effective vaccine for the coronavirus may not be possible. Epidemiological studies reveal the infection of SARS and COVID-19 in children is less frequent and less severe than in adults. Childhood vaccine-mediated cross cellular immunity and immunomodulation might provide protection against the infections of COVID-19. These data suggest that herd immunization with children vaccines in adults may improve the adult cross cellular immunity and immunomodulation and improve their clinical presentation and prognosis. This can be also useful to cope with future pandemics.
目前针对 COVID-19 的疫苗可能需要时间研发，且病毒基因组可能会不断进化和变异，因此针对冠状病毒的通用且有效的疫苗可能无法实现。流行病学研究表明，儿童感染 SARS 和 COVID-19 的频率和严重程度低于成人。儿童疫苗介导的跨细胞免疫和免疫调节可能为 COVID-19 的感染提供保护。这些数据表明，在成人中使用儿童疫苗进行群体免疫可能会改善成人的跨细胞免疫和免疫调节，并改善他们的临床表现和预后。这对于应对未来的大流行也可能是有用的。
