Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Motamed Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Hum Antibodies. 2021;29(1):49-54. doi: 10.3233/HAB-200428.
Coronavirus disease 2019 (COVID-19) has caused a global pandemic in early 2020. This infectious disorder has a heterogeneous course ranging from asymptomatic disorder to a critical situation needing intensive cares. In the current study, we present a report of affected patients admitted in a single hospital in Iran. Eighty-two hospitalized patients with COVID-19 were assessed. Demographic, clinical, and paraclinical parameters were gathered and statistically analyzed. The median age (IQR) of the patients was 57.32 (45.75, 70) years. At primary evaluation, fever was present in 45.12% of the affected individuals. The most common clinical symptoms were dyspnea (81.71%) and cough (65.85%). Totally, 12 (14.63%) and 14 (17.07%) of patients had low and high WBC counts, respectively. Lymphopenia was detected in 36 (43.9%) of patients, while 6 (7.32%) of patients had lymphocytosis. High levels of Il-6 were detected in 4 (4.88%) of patients. CRP levels were elevated in 69 (84.1%) of patients. The median (IQR) of hospitalization was 7 (5, 9) days. Totally, 26 patients (31%) were hospitalized in ICU. All patients were discharged with good health conditions except for one patient who died. The current study shows the heterogeneous clinical manifestations and paraclinical parameters of COVID-19 patients.
2020 年初,冠状病毒病 2019(COVID-19)引发了全球大流行。这种传染病的病程具有异质性,从无症状疾病到需要重症监护的危急情况不等。在本研究中,我们报告了在伊朗一家医院住院的受影响患者。评估了 82 例 COVID-19 住院患者。收集并统计分析了人口统计学、临床和实验室参数。患者的中位数年龄(IQR)为 57.32(45.75,70)岁。在初次评估时,45.12%的患者存在发热。最常见的临床症状是呼吸困难(81.71%)和咳嗽(65.85%)。总共有 12(14.63%)和 14(17.07%)例患者的白细胞计数低和高,分别。36(43.9%)例患者存在淋巴细胞减少症,而 6(7.32%)例患者存在淋巴细胞增多症。4(4.88%)例患者的 Il-6 水平升高。69(84.1%)例患者的 CRP 水平升高。中位(IQR)住院时间为 7(5,9)天。总共有 26 例(31%)患者在 ICU 住院。除一名死亡患者外,所有患者均康复出院。本研究显示了 COVID-19 患者的临床表现和实验室参数具有异质性。