Moholdt Trine, Skarpsno Eivind Schjelderup, Moe Børge, Nilsen Tom Ivar Lund
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
Women's Clinic, St. Olavs Hospital, Trondheim, Norway.
Br J Sports Med. 2020 Sep 28. doi: 10.1136/bjsports-2020-102350.
To examine associations between long-term (11-22 years) adherence to physical activity recommendations and mortality from all causes and from cardiovascular disease.
Prospective population-based study with repeated assessments of self-reported physical activity (1984-86, 1995-97 and 2006-08) and follow-up until the end of 2013.
County of Nord-Trøndelag, Norway.
Men and women aged ≥20 years; 32 811 who participated in 1984-86 and 1995-97; 22 058 in 1984-86 and 2006-08; 31 948 in 1995-97 and 2006-09 and 19 349 in all three examinations (1984-1986, 1995-95 and 2006-08).
All-cause mortality and cardiovascular disease mortality from the national Cause of Death Registry.
Compared with the reference category comprising individuals who adhered to the physical activity recommendations (≥150 min of moderate intensity or ≥60 min of vigorous intensity physical activity per week) over time, individuals who remained inactive (reporting no or very little physical activity) from 1984-86 to 1995-97 had HRs (95% CI) of 1.56 (1.40 to 1.73) for all-cause mortality and 1.94 (1.62 to 2.32) for cardiovascular disease mortality. Individuals who were inactive in 1984-86 and then adhered to recommendations in 2006-08 had HRs of 1.07 (0.85 to 1.35) for all-cause mortality and 1.31 (0.87 to 1.98) for cardiovascular disease mortality. In a subsample of individuals who participated at all three time points, those who were inactive or physically active below the recommended level across three decades (1984-86, 1995-97 and 2006-2008) had an HR of 1.57 (1.22 to 2.03) for all-cause mortality and 1.72 (1.08 to 2.73) for cardiovascular disease mortality.
Individuals who remained, or became, physically inactive had substantially greater risk of all-cause and cardiovascular disease mortality compared with those who met the physical activity recommendations throughout the lifespan.
研究长期（11 - 22年）坚持体育活动建议与全因死亡率和心血管疾病死亡率之间的关联。
基于人群的前瞻性研究，对自我报告的体育活动进行重复评估（1984 - 1986年、1995 - 1997年和2006 - 2008年），并随访至2013年底。
挪威北特伦德拉格郡。
年龄≥20岁的男性和女性；1984 - 1986年和1995 - 1997年参与的有32811人；1984 - 1986年和2006 - 2008年参与的有22058人；1995 - 1997年和2006 - 2009年参与的有31948人，以及在所有三次检查（1984 - 1986年、1995 - 1995年和2006 - 2008年）中参与的19349人。
国家死亡原因登记处的全因死亡率和心血管疾病死亡率。
与长期坚持体育活动建议（每周至少150分钟中等强度或至少60分钟高强度体育活动）的参考类别相比，1984 - 1986年至1995 - 1997年一直不活动（报告无或极少体育活动）的个体，全因死亡率的风险比（95%置信区间）为1.56（1.40至1.73），心血管疾病死亡率的风险比为1.94（1.62至2.32）。1984 - 1986年不活动但在2006 - 2008年坚持建议的个体，全因死亡率的风险比为1.07（0.85至1.35），心血管疾病死亡率的风险比为1.31（0.87至1.98）。在所有三个时间点都参与的个体子样本中，在三个十年（1984 - 1986年、1995 - 1997年和2006 - 2008年）中不活动或体育活动低于推荐水平的个体，全因死亡率的风险比为1.57（1.22至2.03），心血管疾病死亡率的风险比为1.72（1.08至2.73）。
与一生都符合体育活动建议的个体相比，一直不活动或后来变得不活动的个体全因死亡率和心血管疾病死亡率的风险要高得多。
