Department of development and health research, Helse Førde HF, Norway.
Centre for Clinical Research, Haukeland University Hospital, Norway.
Scand J Public Health. 2024 Jun;52(4):476-485. doi: 10.1177/14034948231162729. Epub 2023 Mar 24.
We aimed to explore (a) how different patterns of physical activity (PA) over time (36 years) were associated with all-cause and cause-specific mortality, (b) if the association was similar for males and females and for different body mass levels and (c) how change in PA was associated with mortality for subjects who started out as physically inactive.
The study is based on the prospective population-based cohort Trøndelag Health Study (HUNT) from 1984 to 2020, across four study waves. Data were linked to the Norwegian Cause of Death Registry. There were 123,005 participants, divided into three groups: persistently active, persistently inactive and mixed, with two cut-offs for PA: 60 and 150 minutes per week. The results are reported as cumulative incidence and hazard ratios (HRs).
At 60 minutes of PA per week, 8% of participants were persistently inactive, 15% were persistently active and 77% had a mixed pattern. At 150 minutes, the corresponding numbers were 32%, 2% and 65%. Compared to the persistently inactive group, for the 60-minute cut-off, the mixed group had an all-cause mortality HR of 0.83 (95% confidence interval (CI) 0.70-0.98), and the persistently active group had an HR of 0.51 (95% CI 0.40-0.65). For the 150-minute cut-off, the corresponding HRs were 0.84 (95% CI 0.75-0.94) and 0.48 (95% CI 0.26-0.88). The patterns were similar for males and females and across body mass index levels. Initially inactive participants had lower mortality if they ended up physically active, regardless of their activity level at an intermediate time point.
At least 60 minutes of PA per week was associated with a marked reduction in mortality when this was a lasting habit over three decades. Given that six times as many people reach this less ambitious goal, it is vital to encourage all levels of PA in public health promotion. Any increase in PA during the lifespan is beneficial.
我们旨在探讨（a）随着时间的推移（36 年），不同的体力活动（PA）模式如何与全因和特定原因死亡率相关，（b）这种关联对于男性和女性以及不同的体重水平是否相似，以及（c）对于那些最初不活跃的参与者，PA 的变化与死亡率之间的关系。
本研究基于前瞻性人群为基础的特隆赫姆健康研究（HUNT），时间跨度从 1984 年到 2020 年，共四个研究波次。数据与挪威死因登记处相关联。共有 123005 名参与者，分为三组：持续活跃、持续不活跃和混合组，PA 有两个截止值：每周 60 分钟和 150 分钟。结果以累积发病率和危险比（HR）报告。
每周进行 60 分钟 PA 的参与者中，8%的参与者持续不活跃，15%的参与者持续活跃，77%的参与者具有混合模式。在 150 分钟时，相应的数字分别为 32%、2%和 65%。与持续不活跃组相比，对于 60 分钟的截止值，混合组的全因死亡率 HR 为 0.83（95%置信区间（CI）0.70-0.98），持续活跃组的 HR 为 0.51（95% CI 0.40-0.65）。对于 150 分钟的截止值，相应的 HR 分别为 0.84（95% CI 0.75-0.94）和 0.48（95% CI 0.26-0.88）。这些模式在男性和女性以及不同的体重指数水平上相似。最初不活跃的参与者如果最终变得活跃，无论他们在中间时间点的活动水平如何，死亡率都会降低。
每周至少进行 60 分钟的 PA 与三十年来持续的习惯相关，可显著降低死亡率。鉴于达到这个不那么雄心勃勃的目标的人数是这个数字的六倍，在公共健康促进中鼓励各级别的 PA 至关重要。一生中任何程度的 PA 增加都是有益的。
