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[低剂量¹³⁷Cs慢性实验性内照射下晶状体的年龄相关性辐射敏感性]

[Age-related radiosensitivity of the crystalline lens in chronic experimental internal irradiation with 137Cs at low doses].

作者信息

Gerasimov V I, Ermolaeva-Makovskaia A P, Ramzaev P V, Troitskaia M N

出版信息

Med Radiol (Mosk). 1987 Jun;32(6):61-3.

PMID:3298917
Abstract

Internal whole-body irradiation of mice for 1 year with incorporated 137Cs at a dose of 0.5 eV was shown to make a significant cataractogenic effect on the lens. By annual rate this dose exceeded the existing maximum permissible dose only three times and was less than 10% of a cumulative dose for professionals having to do with ionizing radiation which they can accumulate at the maximum permissible dose level in annual irradiation for 50 years. The time of recorded lenticular opacity reduced and a degree of observed changes increased in the study groups as compared to the unirradiated control group indicating the involvement of a radiation factor in their development. More pronounced sensitivity of the mouse lens to chronic radiation exposure in the second half of the life than in the first half was noted.

摘要

用剂量为0.5电子伏特的掺入137铯对小鼠进行为期1年的全身内照射,结果表明对晶状体有显著的致白内障作用。按年剂量率计算,该剂量仅超过现有最大允许剂量3倍,且不到从事电离辐射工作的专业人员在50年的年度照射中以最大允许剂量水平累积剂量的10%。与未受照射的对照组相比,研究组中记录到晶状体混浊的时间缩短,观察到的变化程度增加,这表明辐射因素参与了其发展。研究发现,小鼠晶状体在生命后半期对慢性辐射暴露的敏感性比前半期更明显。

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