18F FDG PET/CT检查后意外诊断为新型冠状病毒肺炎：病例系列报道
Accidental diagnosis of COVID-19 pneumonia after 18F FDG PET/CT: a case series.
作者信息
Olivari Laura, Riccardi Niccolò, Rodari Paola, Buonfrate Dora, Diodato Stefania, Formenti Fabio, Angheben Andrea, Salgarello Matteo
机构信息
Department of Nuclear Medicine, IRCCS Sacro Cuore Don Calabria Hospital, Via Don Angelo Sempreboni, 5, Cap 37024 Negrar Di Valpolicella, VR Italy.
Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar Di Valpolicella, Verona, Italy.
出版信息
Clin Transl Imaging. 2020;8(5):393-400. doi: 10.1007/s40336-020-00388-8. Epub 2020 Sep 24.
PURPOSE
The aim of this case series is to illustrate possible [18F]-FDG uptake patterns associated to COVID-19.
METHODS
Retrospective assessment of all Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scans performed for any clinical / oncological reason from 1st April 2020 to 30th April 2020. Results of PCR testing for SARS-CoV-2 were retrieved for all patients with lung consolidations and/or peripheral ground glass opacities characterized by increased metabolism to evaluate any possible association with the viral infection.
RESULTS
Seven (4%) out of 172 FDG-PET scans were included. Six out of seven patients (85%) had positive RT-PCR for SARS-CoV-2, while one patient (15%) had possible (not PCR confirmed) COVID-19 pneumonia.
CONCLUSION
Suspicious accidental COVID-19 findings in Nuclear Medicine Department need to be reported and appropriately evaluated to implement proper supportive treatment and infection control measures.
目的
本病例系列的目的是阐述与新型冠状病毒肺炎（COVID-19）相关的可能的[18F]-氟代脱氧葡萄糖（FDG）摄取模式。
方法
回顾性评估2020年4月1日至2020年4月30日期间因任何临床/肿瘤原因进行的所有氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（18F-FDG PET/CT）。检索所有肺部实变和/或外周磨玻璃影且代谢增加患者的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）聚合酶链反应（PCR）检测结果，以评估与病毒感染的任何可能关联。
结果
172例FDG-PET扫描中有7例（4%）被纳入。7例患者中有6例（85%）SARS-CoV-2的逆转录PCR（RT-PCR）检测呈阳性，而1例患者（15%）可能患有（未通过PCR确诊）COVID-19肺炎。
结论
核医学科中可疑的偶发COVID-19发现需要报告并进行适当评估，以实施适当的支持治疗和感染控制措施。
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