Srour Marissa K, Kim Sungjin, Amersi Farin, Giuliano Armando E, Chung Alice
Department of Surgery, Division of Surgical Oncology, Cedars-Sinai Medical Center, 310 North San Vicente Blvd, Los Angeles, CA, 90048, USA.
Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ann Surg Oncol. 2021 Apr;28(4):2212-2218. doi: 10.1245/s10434-020-09159-1. Epub 2020 Sep 28.
Radioactive seed localization (RSL) and the Savi Scout radar (SSR) are newer alternatives to wire-guided localization (WL) for nonpalpable breast lesions.
The aim of this study was to compare three localization devices when multiple devices were used for preoperative localization for breast surgery.
Between July 2017 and July 2018, 68 patients had a partial mastectomy (n = 54) or breast biopsy (n = 14) with preoperative image-guided localization using multiple wires or device placement for nonpalpable lesions. Operative timing, outcomes, and 30-day complications were evaluated.
Overall, 41 patients (60%) had WL, 11 patients (16%) had RSL, and 16 patients (24%) had SSR localization. Fifty-four patients (79.4%) had localization of two lesions and 13 patients (19.1%) had localization of three lesions. Twenty-three patients (33.8%) had a lesion that was bracketed. There was no difference in retained biopsy clip among the groups (average 7.4%; p = 0.962). For operations performed in the hospital, there was no difference in operative time among the groups, with a median of 77.5 min (p = 0.705) or total perioperative time of 508 min (p = 0.210). Among operations with delayed start times, there was a longer average delay of 95.5 min in WL, compared with 42 min in SSR (p = 0.004). A greater volume of tissue was excised in the WL group (29.5 g WL vs. 15.9 g RSL vs. 12.1 g SSR; p = 0.022). There was no difference in positive margin rate and 30-day complications among groups.
SSR and RSL can be used to localize multiple breast lesions, with no difference in positive margin rates or complications and less tissue excised compared with WL.
对于不可触及的乳腺病变,放射性种子定位(RSL)和Savi Scout雷达(SSR)是线引导定位(WL)的更新替代方法。
本研究的目的是比较在乳腺手术术前定位中使用多种设备时的三种定位设备。
2017年7月至2018年7月期间,68例患者接受了保乳手术(n = 54)或乳腺活检(n = 14),对不可触及的病变采用术前影像引导定位,使用多根导线或设备放置。评估手术时机、结果和30天并发症。
总体而言,41例患者(60%)采用WL,11例患者(16%)采用RSL,16例患者(24%)采用SSR定位。54例患者(79.4%)对两个病变进行了定位,13例患者(19.1%)对三个病变进行了定位。23例患者(33.8%)有一个病变被包围。各组间活检夹留存率无差异(平均7.4%;p = 0.962)。对于在医院进行的手术,各组间手术时间无差异,中位数为77.5分钟(p = 0.705)或围手术期总时间为508分钟(p = 0.210)。在延迟开始时间的手术中,WL组的平均延迟时间更长,为95.5分钟,而SSR组为42分钟(p = 0.004)。WL组切除的组织量更大(WL组29.5克,RSL组15.9克,SSR组12.1克;p = 0.022)。各组间切缘阳性率和30天并发症无差异。
SSR和RSL可用于定位多个乳腺病变,切缘阳性率或并发症无差异,与WL相比切除的组织更少。