Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Oklahoma/Texas/and Arkansas Blood Institute, Oklahoma City, Oklahoma, USA.
Transfusion. 2020 Dec;60(12):2828-2833. doi: 10.1111/trf.16118. Epub 2020 Oct 8.
Arkansas is a rural state of 3 million people. It is ranked fifth for poverty nationally. The first case of coronavirus disease 2019 (COVID-19) in Arkansas occurred on 11 March 2020. Since then, approximately 8% of all Arkansans have tested positive. Given the resource limitations of Arkansas, COVID-19 convalescent plasma (CCP) was explored as a potentially lifesaving, therapeutic option. Therefore, the Arkansas Initiative for Convalescent Plasma was developed to ensure that every Arkansan has access to this therapy.
This brief report describes the statewide collaborative response from hospitals, blood collectors, and the Arkansas Department of Health (ADH) to ensure that CCP was available in a resource-limited state.
Early contact tracing by ADH identified individuals who had come into contact with "patient zero" in early March. Within the first week, 32 patients tested positive for COVID-19. The first set of CCP collections occurred on 9 April 2020. Donors had to be triaged carefully in the initial period, as many had recently resolved their symptoms. From our first collections, with appropriate resource and inventory management, we collected sufficient CCP to provide the requested number of units for every patient treated with CCP in Arkansas.
The Arkansas Initiative, a statewide effort to ensure CCP for every patient in a resource-limited state, required careful coordination among key players. Collaboration and resource management was crucial to meet the demand of CCP products and potentially save lives.
阿肯色州是一个拥有 300 万人口的农村州，其贫困率在全美排名第五。阿肯色州首例 2019 年冠状病毒病（COVID-19）病例于 2020 年 3 月 11 日出现。此后，大约 8%的阿肯色人检测呈阳性。鉴于阿肯色州资源有限，COVID-19 恢复期血浆（CCP）被探索为一种潜在的救生治疗选择。因此，阿肯色州恢复期血浆倡议得以开发，以确保每个阿肯色人都能获得这种治疗。
本简要报告描述了全州范围内医院、血液采集者和阿肯色州卫生部（ADH）之间的协作反应，以确保在资源有限的州中提供 CCP。
ADH 的早期接触者追踪确定了 3 月早些时候与“零号病人”接触过的人。在第一周内，有 32 名患者 COVID-19 检测呈阳性。第一批 CCP 采集于 2020 年 4 月 9 日进行。在最初阶段，必须仔细对捐赠者进行分类，因为许多人最近已缓解了症状。通过我们的首次采集，通过适当的资源和库存管理，我们收集了足够的 CCP，为阿肯色州接受 CCP 治疗的每位患者提供了所需数量的单位。
阿肯色州倡议是一项全州范围内的努力，旨在确保资源有限的州中每个患者都能获得 CCP，这需要关键参与者之间的精心协调。协作和资源管理对于满足 CCP 产品的需求并可能挽救生命至关重要。
