Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xiangya School of Medicine, Central South University, Changsha, China.
Heart Surg Forum. 2020 Sep 29;23(5):E703-E711. doi: 10.1532/hsf.3149.
Catheter ablation for atrial fibrillation (AF) has been gaining popularity; however, the trend of inflammatory response markers in patients treated with different catheter ablation strategies over time and their predictability of AF recurrence remain unknown.
A total of 210 patients with AF were enrolled and grouped according to surgical mode as follows: freeze group, RF group, and freeze3D group. The subjects were tested for related indexes before and after surgery. To determine AF recurrence during follow up, 24-h ambulatory electrocardiography was performed at two, three, six, and 12 months after surgery.
The inflammation indexes of the three groups peaked between one and three days after surgery but fell at different time points (P < .05). The recurrence rate of paroxysmal atrial fibrillation (PAF) was positively correlated with the increase in the percentage of white blood cells and neutrophils after surgery (P < .05).
The postoperative inflammation indices peaked and fell at different time points after different catheter ablation methods. In addition, the recurrence rate of AF in patients treated with freeze3D is lower.
导管消融术治疗心房颤动（AF）越来越受欢迎；然而，目前尚不清楚随着时间的推移，采用不同导管消融策略的患者的炎症反应标志物的趋势及其对 AF 复发的预测性。
共纳入 210 例 AF 患者，并根据手术方式分为冷冻组、RF 组和冷冻 3D 组。手术前后对患者进行相关指标检测。通过术后 2、3、6 和 12 个月的 24 小时动态心电图监测，确定随访期间 AF 的复发情况。
三组的炎症指标在术后 1-3 天达到峰值，但下降时间不同（P<.05）。阵发性心房颤动（PAF）的复发率与术后白细胞和中性粒细胞百分比的升高呈正相关（P<.05）。
不同导管消融方法后，术后炎症指标在不同时间达到峰值并下降。此外，冷冻 3D 治疗的 AF 复发率较低。
