Sundar Serendipity Foundation, Chennai, India. Email:
The Micronutrient Research Foundation, Chennai, India.
Asia Pac J Clin Nutr. 2020;29(3):577-583. doi: 10.6133/apjcn.202009_29(3).0017.
To improve the iron status of school children through noon meals prepared using a multiple micronutrient-fortified salt.
Children from a randomly selected school who consumed (intervention) and did not consume (reference) a noon meal prepared using a multiple micronutrient- fortified salt were studied over 1 year. A pre-post-test design for children aged 5-17years in reference (n=100) and intervention (n=128) groups was used. Levels of serum ferritin, soluble transferrin receptor (sTfR), alpha glycoprotein (AGP), and C-reactive protein (CRP) were assessed at baseline and at 1 year. In a subsample, urinary iodine was assessed.
sTfR decreased in the intervention group (-0.80 mg/L) but increased in the reference group (0.47 mg/L) at 1 year (p=0.0001).Body iron stores (BIS) increased in the intervention group (0.09 mg/kg body weight) and decreased (-0.58 mg/kg body weight) in the reference group at 1 year (p=0.028).These findings indicate an increase in iron deficiency in the reference group and a decrease in the intervention group. However, no changes in serum ferritin and urinary iodine were observed in either group or between groups.
Iron status can be improved in schoolchildren in Tamil Nadu by increasing the amount of micronutrients in the fortified salt used for preparing noon-time school meals.
通过在午餐中使用强化了多种微量营养素的盐来改善学童的铁营养状况。
在为期 1 年的时间里,对随机选择的一所学校中食用(干预组)和未食用(参照组)强化了多种微量营养素的盐制成的午餐的儿童进行了研究。采用预-后测试设计,对 5-17 岁的参照组(n=100)和干预组(n=128)的儿童进行了研究。在基线和 1 年时,评估血清铁蛋白、可溶性转铁蛋白受体(sTfR)、α糖蛋白(AGP)和 C 反应蛋白(CRP)的水平。在亚样本中,评估了尿碘水平。
在干预组,sTfR 在 1 年内下降(-0.80mg/L),而在参照组则上升(0.47mg/L)(p=0.0001)。干预组的铁储备量(BIS)增加(0.09mg/kg 体重),参照组则下降(-0.58mg/kg 体重)(p=0.028)。这些结果表明,参照组的缺铁症增加,而干预组的缺铁症减少。然而,血清铁蛋白和尿碘在两组中均未发生变化,组间也未发生变化。
通过增加在午餐中使用的强化盐中的微量营养素含量,可以改善泰米尔纳德邦学童的铁营养状况。