Su Chang, Chen Danqing
Obstetrical Department, Women's Hospital,School of Medicine, Zhejiang University, Hangzhou, China.
Medicine (Baltimore). 2020 Sep 25;99(39):e22499. doi: 10.1097/MD.0000000000022499.
The clinical treatment is complicated for patients with placenta previa who must terminate pregnancy due to fetal malformation, death, or inevitable abortion in the second trimester. It is difficult to manage excessive bleeding during pregnancy termination; and those patients face risks of removing the uterus, infection and other complications.
Two patients had placenta previa in the second trimester. Both cases had to terminate pregnancy. Case 1 patient had intrauterine fetal death. Case 2 patient had life-threatening vaginal bleeding. Both patients had bleeding and their cervix was not mature during vaginal delivery.
After hospitalization, placenta previa was confirmed by magnetic resonance imaging for case 1 patient. Placenta previa was confirmed by ultrasound examination for case 2 patient. Both patients had to terminate pregnancy.
We designed a new procedure using a cervical ripening balloon to reduce the risks during pregnancy termination for patients with placenta previa. A cervical ripening balloon was inserted through the placenta and placed between the fetus and placenta; external force was applied to keep the cervical ripening balloon pressing against the placenta that covers the cervical os. The cervical ripening balloon dilated the cervix, quickly reduced bleeding, and induced vaginal delivery during pregnancy termination for patients with placenta previa. This method was applied to 2 patients with placenta previa who must terminate pregnancy.
Using the new method, both patients had a successful pregnancy termination and vaginal delivery with minimal bleeding. Total time from the balloon placement to the end of the delivery was about 3 hours. The procedure only used a cervical ripening balloon without uterine artery embolization needed. The fetus was delivered through the vagina; and the uterus was fully retained. There was no postpartum infection.
This new method using a cervical ripening balloon could be a quick and effective way to reduce the risks during pregnancy termination for patients with placenta previa. It is especially helpful in emergency situations with minimal requirements of personnel and equipment. Our study showed great potential of this new utilization of a cervical ripening balloon, and is worthy of further research.
对于因胎儿畸形、死亡或孕中期难免流产而必须终止妊娠的前置胎盘患者,临床治疗较为复杂。终止妊娠期间难以控制大出血;这些患者面临子宫切除、感染及其他并发症的风险。
两名患者在孕中期患有前置胎盘。两例均必须终止妊娠。病例1患者胎儿宫内死亡。病例2患者出现危及生命的阴道出血。两名患者在阴道分娩时均有出血且宫颈未成熟。
病例1患者住院后经磁共振成像确诊为前置胎盘。病例2患者经超声检查确诊为前置胎盘。两名患者均必须终止妊娠。
我们设计了一种新方法,使用宫颈成熟球囊以降低前置胎盘患者终止妊娠期间的风险。将宫颈成熟球囊经胎盘插入并置于胎儿与胎盘之间;施加外力使宫颈成熟球囊压迫覆盖宫颈内口的胎盘。宫颈成熟球囊扩张宫颈,迅速减少出血,并诱导前置胎盘患者在终止妊娠期间经阴道分娩。该方法应用于2例必须终止妊娠的前置胎盘患者。
采用新方法,两名患者均成功终止妊娠并经阴道分娩,出血极少。从放置球囊到分娩结束的总时间约为3小时。该操作仅使用宫颈成熟球囊,无需子宫动脉栓塞。胎儿经阴道娩出;子宫得以完全保留。无产后感染。
这种使用宫颈成熟球囊的新方法可能是降低前置胎盘患者终止妊娠期间风险的一种快速有效的方法。在人员和设备需求最少的紧急情况下尤其有用。我们的研究显示了这种宫颈成熟球囊新应用的巨大潜力,值得进一步研究。