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小体积子宫肌瘤对高危妊娠妊娠结局的影响。

The Effect of Small Size Uterine Fibroids on Pregnancy Outcomes in High-risk Pregnancies.

机构信息

Division of Perinatology, Department of Obstetrics and Gynecology, Ankara, Turkey.

Department of Biology, Hacettepe University, Ankara, Turkey.

出版信息

Rev Bras Ginecol Obstet. 2020 Sep;42(9):535-539. doi: 10.1055/s-0040-1713913. Epub 2020 Sep 29.

DOI:10.1055/s-0040-1713913
PMID:32992356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10309216/
Abstract

OBJECTIVE

To evaluate the obstetric outcomes of singleton high-risk pregnancies with a small size uterine fibroid.

METHODS

This retrospective cohort study was conducted among 172 high-risk pregnant women who were followed-up by a single surgeon between 2016 and 2019. Pregnant women with preconceptionally diagnosed small size (< 5 cm) single uterine fibroids ( = 25) were compared with pregnant women without uterine fibroids ( = 147) in terms of obstetric outcomes.

RESULTS

There was no statistically significant difference between the groups in terms of adverse pregnancy outcomes. The size of the fibroids was increased in 60% of the cases, and the growth percentage of the fibroids was 25% during pregnancy. Intrapartum and short-term complication was not observed in women who underwent cesarean myomectomy.

CONCLUSION

Small size uterine fibroids seem to have no adverse effect on pregnancy outcomes even in high-risk pregnancies, and cesarean myomectomy may be safely performed in properly selected cases.

摘要

目的

评估患有小体积子宫肌瘤的单胎高危妊娠的产科结局。

方法

本回顾性队列研究纳入了 2016 年至 2019 年间由同一位外科医生随访的 172 名高危孕妇。将孕前诊断为小体积(<5cm)单发子宫肌瘤的孕妇(n=25)与无子宫肌瘤的孕妇(n=147)进行比较,观察产科结局。

结果

两组不良妊娠结局无统计学差异。60%的病例中肌瘤增大,怀孕期间肌瘤生长百分比为 25%。行剖宫产子宫肌瘤切除术的孕妇未发生分娩期和短期并发症。

结论

小体积子宫肌瘤似乎不会对妊娠结局产生不良影响,即使是高危妊娠,在适当选择的情况下,行剖宫产子宫肌瘤切除术是安全的。

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J Invest Surg. 2021 Oct;34(10):1104-1107. doi: 10.1080/08941939.2020.1742402. Epub 2020 Mar 31.
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Myoma praevia and pregnancy.前置肌瘤与妊娠
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Impact of extractable nuclear antigen, anti-double stranded DNA, antiphospholipid antibody, and anticardiolipin antibody positivity on obstetrical complications and pregnancy outcomes.可提取核抗原、抗双链DNA、抗磷脂抗体及抗心磷脂抗体阳性对产科并发症及妊娠结局的影响。
Hum Antibodies. 2019;27(2):135-141. doi: 10.3233/HAB-180359.
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Cesarean Myomectomy: Necessity or Opportunity?剖宫产子宫肌瘤切除术:必要之举还是机遇之选?
J Obstet Gynaecol India. 2018 Dec;68(6):432-436. doi: 10.1007/s13224-018-1114-8. Epub 2018 Mar 23.
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Uterine fibroid size modifications during pregnancy and puerperium: evidence from the first systematic review of literature.孕期及产褥期子宫肌瘤大小的变化:来自首次文献系统综述的证据
Arch Gynecol Obstet. 2018 Apr;297(4):823-835. doi: 10.1007/s00404-017-4621-4. Epub 2017 Dec 13.
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J Minim Invasive Gynecol. 2016 Jul-Aug;23(5):702-6. doi: 10.1016/j.jmig.2016.03.018. Epub 2016 Mar 31.
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