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通过标准化随访治疗教育和远程监测解决方案对慢性心力衰竭患者进行门诊管理的益处:一项针对159例患者的原创性研究。

Benefit of Ambulatory Management of Patients with Chronic Heart Failure by Protocolized Follow-Up Therapeutic Education and Remote Monitoring Solution: An Original Study in 159 Patients.

作者信息

Jenneve Anne, Lorenzo-Villalba Noel, Courdier Guy, Talha Samy, Séverac François, Zulfiqar Abrar-Ahmad, Arnold Patrick, Lang Philippe, Roul Gérald, Andrès Emmanuel

机构信息

Unité de Suivi des Patients Insuffisants Cardiaques, Clinique du Diaconat, 68067 Mulhouse, France.

Service de Médecine Interne, Diabète et Maladies Métaboliques, Clinique Médicale B, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.

出版信息

J Clin Med. 2020 Sep 25;9(10):3106. doi: 10.3390/jcm9103106.

Abstract

This study sought to determine whether the implementation of regular and structured follow-up of patients with chronic heart failure (CHF), combined with therapeutic education and remote monitoring solution, leads to better management. This was a single-center retrospective study conducted in a cohort of patients with proven CHF who were followed up in the Mulhouse region (France) between January 2016 and December 2017 by the Unité de Suivi des Patients Insuffisants Cardiaques (USICAR) unit. These patients received regular protocolized follow-up, a therapeutic education program, and several used a telemedicine platform for a two-year period. The primary endpoint was the number of days hospitalized for heart failure (HF) per patient per year. The main secondary endpoints included the number of days hospitalized for a heart condition other than HF and the number of hospital stays for HF per patient. These endpoints were collected during the year preceding enrollment, at one year of follow-up, and at two years of follow-up. The remote monitoring solution was evaluated on the same criterion. Overall, 159 patients with a mean age of 72.9 years were included in this study. They all had CHF, mainly NYHA Class I-II (88.7%), predominantly of ischemic origin (50.9%), and with altered left ventricular ejection fraction in 69.2% of cases. The mean number of days hospitalized for HF per patient per year was 8.33 (6.84-10.13) in the year preceding enrollment, 2.6 (1.51-4.47) at one year of follow-up, and 2.82 at two years of follow-up (1.30-6.11) ( < 0.01 for both comparisons). The mean number of days hospitalized for a heart condition other than HF was 1.73 (1.16-2.6), 1.81 (1.04-3.16), and 1.32 (0.57-3.08), respectively ( = ns). The percentage of hospitalization for HF for each patient was 69.5% (60.2-77.4), 16.2% (10-25.2), and 19.3% (11-31.8), respectively ( < 0.001 for both comparisons). In the group telemedicine, the mean number of days hospitalized for HF per patient per year was 8.33 during the year preceding enrollment, 2.3 during the first year of follow-up, and 1.7 during the second. This difference was significant ( < 0.001). The "number of days hospitalized for a heart condition other than HF" was significantly reduced in the group of patient's beneficiating from the remote monitoring solution. This study demonstrates the value of a protocolized follow-up associated with a therapeutic optimization, therapeutic education program, and the use of a remote monitoring solution to improve the management of ambulatory patients with CHF, particularly of moderate severity.

摘要

本研究旨在确定对慢性心力衰竭(CHF)患者实施定期且结构化的随访,并结合治疗教育和远程监测解决方案,是否能带来更好的管理效果。这是一项单中心回顾性研究,对一组确诊为CHF的患者进行了研究,这些患者于2016年1月至2017年12月在法国米卢斯地区由心脏衰竭患者随访单位(USICAR)进行随访。这些患者接受了定期的标准化随访、治疗教育计划,并且有部分患者在两年时间内使用了远程医疗平台。主要终点是每位患者每年因心力衰竭(HF)住院的天数。主要次要终点包括因非HF心脏疾病住院的天数以及每位患者因HF住院的次数。这些终点数据在入组前一年、随访一年和随访两年时收集。远程监测解决方案也基于相同标准进行评估。总体而言,本研究纳入了159名平均年龄为72.9岁的患者。他们均患有CHF,主要为纽约心脏协会(NYHA)I-II级(88.7%),主要病因是缺血性(50.9%),69.2%的病例左心室射血分数改变。入组前一年每位患者每年因HF住院的平均天数为8.33(6.84 - 10.13)天,随访一年时为2.6(1.51 - 4.47)天,随访两年时为2.82(1.30 - 6.11)天(两次比较均P<0.01)。因非HF心脏疾病住院的平均天数分别为1.73(1.16 - 2.6)天、1.81(1.04 - 3.16)天和1.32(0.57 - 3.08)天(P = 无统计学意义)。每位患者因HF住院的百分比分别为69.5%(60.2 - 77.4)、16.2%(10 - 25.2)和19.3%(11 - 31.8)(两次比较均P<0.001)。在远程医疗组中,入组前一年每位患者每年因HF住院的平均天数为8.33天,随访第一年为2.3天,第二年为1.7天。这种差异具有统计学意义(P<0.001)。在受益于远程监测解决方案的患者组中,“因非HF心脏疾病住院的天数”显著减少。本研究证明了标准化随访与治疗优化、治疗教育计划以及使用远程监测解决方案相结合,对于改善门诊CHF患者尤其是中度严重程度患者的管理具有价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be0f/7599658/09a9162ba134/jcm-09-03106-g001.jpg

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