Oxford Transplant Centre, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
Renal Transplantation and Nephrology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
J Vasc Access. 2021 Nov;22(6):1021-1025. doi: 10.1177/1129729820961972. Epub 2020 Sep 30.
Intestinal failure (IF) patients are dependent on central venous access to receive parenteral nutrition. Longstanding central venous catheters are associated with life-threatening complications including infections and thromboses resulting in multiple line exchanges and the development ofprogressive central venous stenosis or occlusion. The Haemodialysis Reliable Outflow (HeRO) graft is an arterio-venous device that has been successfully used in haemodialysis patients with 'end-stage vascular access'. We describe a case series of HeRO graft use in patients with IF and end-stage vascular access. Four HeRO grafts were inserted into IF patients with end-stage vascular access to facilitate or support intestinal transplantation. In all patients the HeRO facilitated immediate vascular access, supporting different combinations of parenteral nutrition, intravenous medications, fluids or renal replacement therapy with no bloodstream infections. In a highly complex group of IF patients with central venous stenosis/occlusion limiting conventional venous access or at risk of life-threatening catheter-related complications, a HeRO graft can be a feasible alternative.
肠衰竭(IF)患者依赖中心静脉通路接受肠外营养。长期留置的中心静脉导管与危及生命的并发症相关,包括感染和血栓形成,导致多次更换导管并逐渐出现进行性中心静脉狭窄或闭塞。血液透析可靠流出(HeRO)移植物是一种动静脉装置,已成功用于“终末期血管通路”的血液透析患者。我们描述了一组使用 HeRO 移植物治疗 IF 和终末期血管通路患者的病例系列。将四个 HeRO 移植物插入终末期血管通路的 IF 患者体内,以促进或支持肠移植。在所有患者中,HeRO 立即为血管通路提供了便利,支持不同组合的肠外营养、静脉内药物、液体或肾脏替代治疗,没有血流感染。对于一组具有中心静脉狭窄/闭塞限制常规静脉通路或有发生危及生命的导管相关并发症风险的高度复杂 IF 患者,HeRO 移植物可能是一种可行的替代方案。