Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Medaffcon Oy, Espoo, Finland.
J Headache Pain. 2020 Sep 29;21(1):118. doi: 10.1186/s10194-020-01185-4.
A global My Migraine Voice survey was conducted in 31 countries among 11,266 adults who suffered from ≥4 monthly migraine days (MMD). The aim of this retrospective observational survey-based study was to analyse the country specific results in Finland in order to understand the impact of migraine based on disease severity.
The included participants (3%, n = 338/11,266) were stratified by mean MMDs into 4 ≤ MMD < 8 (n = 133), 8 ≤ MMD < 15 (n = 139) and MMD ≥ 15 (n = 66) subgroups. Comorbidities, migraine-related emotional burden and impact on daily living and work productivity and activity impairment (WPAI) were assessed. Subgroup analysis on healthcare resource utilization (HCRU) due to migraine was assessed by visits to healthcare practitioners (HCPs) during the past 6 months and by hospitalizations and emergency room (ER) visits during the past 12 months. The group difference was tested using the one-way ANOVA and for categorical variables using the Chi-squared test. The association between HCRU and MMD and number of comorbidities was assessed using negative binomial regression analysis.
Mean age was 44 years, 93% were women and 67% (n = 227) were employed. Chronic migraine (CM, MMD ≥ 15) was reported in 19.5% of the respondents. The negative impact on daily functioning and emotional burden increased significantly by migraine frequency. Mean number of comorbidities was 2.4, and mean number of HCP visits during the previous 6 months was 5.9. Increase in migraine frequency and comorbidities was associated with higher HCRU. Eighty-eight percent of the respondents reported negative impact on working life and 52% experienced overall work productivity impairment. Over previous month, the mean number of missed working days for all respondents was 2.8 days of which 54% were paid sick leave days, and in CM up to 6.0 days and 30%, respectively. Both absenteeism and presenteeism were higher in the CM group.
The emotional and functional burden was high, and the societal burden increased by frequency and severity of migraine, as shown by higher HCRU and reduced work productivity. There is a need to improve quality of care in migraine and improve migraine management related issues in both healthcare and society in Finland.
一项针对全球 31 个国家、11266 名每月偏头痛发作≥4 天的成年人进行的“我的偏头痛之声”全球调查。本回顾性观察性研究旨在分析芬兰的国家特定结果，以了解基于疾病严重程度的偏头痛的影响。
根据平均偏头痛发作天数（MMD），将纳入的参与者（3%，n=338/11266）分为 4≤MMD<8（n=133）、8≤MMD<15（n=139）和 MMD≥15（n=66）亚组。评估合并症、偏头痛相关情绪负担以及对日常生活和工作生产力和活动障碍（WPAI）的影响。通过过去 6 个月内就诊于医疗保健提供者（HCP）的次数和过去 12 个月内的住院和急诊室（ER）就诊次数评估偏头痛相关的医疗保健资源利用（HCRU）的亚组分析。使用单因素方差分析检验组间差异，使用卡方检验检验分类变量。使用负二项回归分析评估 HCRU 与 MMD 和合并症数量之间的关系。
平均年龄为 44 岁，93%为女性，67%（n=227）为在职人员。19.5%的受访者报告有慢性偏头痛（CM，MMD≥15）。偏头痛发作频率的增加显著导致日常生活功能和情绪负担的负面影响增加。平均合并症数量为 2.4，过去 6 个月的平均 HCP 就诊次数为 5.9。偏头痛发作频率和合并症的增加与更高的 HCRU 相关。88%的受访者报告对工作生活有负面影响，52%的人工作生产力受到影响。在过去一个月，所有受访者平均缺工天数为 2.8 天，其中 54%为带薪病假，CM 组分别为 6.0 天和 30%。旷工和在职缺勤在 CM 组中均较高。
情绪和功能负担较高，偏头痛的频率和严重程度增加导致 HCRU 增加和工作生产力降低，社会负担增加。芬兰需要改善偏头痛的护理质量，并改善医疗保健和社会中与偏头痛管理相关的问题。
