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瑞芬太尼快通道麻醉对成人经胸室间隔缺损封堵术术后镇痛和镇静的影响。

Effect of remifentanil-based fast-track anesthesia on postoperative analgesia and sedation in adult patients undergoing transthoracic device closure of ventricular septal defect.

机构信息

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China.

出版信息

J Cardiothorac Surg. 2020 Sep 29;15(1):281. doi: 10.1186/s13019-020-01339-0.

DOI:10.1186/s13019-020-01339-0
PMID:32993714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7523253/
Abstract

OBJECTIVE

To investigate the effect of remifentanil-based fast-track anesthesia on analgesia and sedation after transthoracic device closure of ventricular septal defects (VSDs) in adult patients.

METHODS

A retrospective analysis was performed on 59 patients aged 21-53 years who underwent transthoracic device closure of VSDs from January 2019 to September 2019. According to the different anesthesia strategies, the patients were divided into the R group (using remifentanil-based anesthesia, n = 33) and the S group (using sufentanil-based anesthesia, n = 26). Patient-related clinical data, postoperative analgesia, and sedation scores were collected and analyzed.

RESULTS

There was no significant difference in age, gender, body weight, and operation time between the group R and the group S (P > 0.05). There was also no significant difference in intraoperative hemodynamic changes, BIS scores, postoperative analgesia, and sedation scores between the two groups (P > 0.05). The duration of mechanical ventilation, the length of ICU stay, and hospital stay in the group R were significantly lower than those in the group S (P < 0.05).

CONCLUSION

Remifentanil-based fast-track anesthesia is effective for adult patients undergoing transthoracic device closure of VSDs, which may shorten the mechanical ventilation duration, the ICU and hospital stay of patients.

摘要

目的

探讨瑞芬太尼快通道麻醉对成人经胸室间隔缺损(VSD)封堵术后镇痛和镇静的影响。

方法

回顾性分析 2019 年 1 月至 2019 年 9 月 53 例行经胸 VSD 封堵术的 21~53 岁患者的临床资料。根据不同麻醉策略,将患者分为瑞芬太尼组(n=33)和舒芬太尼组(n=26)。记录患者一般资料、术中血流动力学变化、脑电双频指数(BIS)、术后镇痛镇静评分及术后机械通气时间、ICU 停留时间和住院时间。

结果

两组患者年龄、性别、体质量、手术时间比较差异无统计学意义(P>0.05)。两组患者术中血流动力学变化、BIS 评分、术后镇痛镇静评分比较差异无统计学意义(P>0.05)。瑞芬太尼组患者术后机械通气时间、ICU 停留时间及住院时间均短于舒芬太尼组(P<0.05)。

结论

瑞芬太尼快通道麻醉用于成人经胸 VSD 封堵术,可缩短患者术后机械通气时间、ICU 停留时间及住院时间。

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