Xu Ning, Sun Kai-Peng, Huang Shu-Ting, Chen Liang-Wan, Cao Hua, Chen Qiang
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China.
J Card Surg. 2021 Feb;36(2):637-642. doi: 10.1111/jocs.15294. Epub 2021 Jan 6.
This study aimed to evaluate the analgesic and sedative effects of remifentanil-based fast-track cardiac anesthesia in children undergoing transthoracic device closure of ventricular septal defects (VSDs).
A retrospective analysis was conducted on 62 children who underwent transthoracic device closure of VSDs from May 2019 to August 2019. The patients were divided into two groups based on the anesthesia methods: group F was given remifentanil-based fast-track cardiac anesthesia, and Group C was given conventional anesthesia. Patient-related clinical data, postoperative analgesia scores, and sedation scores were collected and analyzed.
There was no significant difference in intraoperative hemodynamic changes, bispectral index values, postoperative analgesia scores, sedation scores, or the incidence of adverse events between the two groups. Compared with Group C, the duration of mechanical ventilation and the length of intensive care unit (ICU) and hospital stay in group F were significantly lower.
Remifentanil-based fast-track anesthesia can be safely applied in children undergoing transthoracic device closure of VSDs, with acceptable postoperative analgesia and sedation effects and shorter mechanical ventilation times and ICU and hospital stays compared with conventional anesthesia.
本研究旨在评估瑞芬太尼用于小儿经胸室间隔缺损（VSD）封堵术快速心脏麻醉的镇痛和镇静效果。
对2019年5月至2019年8月期间接受经胸VSD封堵术的62例患儿进行回顾性分析。根据麻醉方法将患者分为两组：F组采用瑞芬太尼快速心脏麻醉，C组采用传统麻醉。收集并分析患者相关临床资料、术后镇痛评分和镇静评分。
两组术中血流动力学变化、脑电双频指数值、术后镇痛评分、镇静评分或不良事件发生率无显著差异。与C组相比，F组机械通气时间、重症监护病房（ICU）住院时间和住院总时长显著缩短。
瑞芬太尼快速麻醉可安全应用于小儿经胸VSD封堵术，术后镇痛和镇静效果良好，与传统麻醉相比，机械通气时间、ICU住院时间和住院总时长更短。
