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人工智能在抗击 COVID-19 中的新兴作用。

The Emerging Role of Artificial Intelligence in the Fight Against COVID-19.

机构信息

Medway NHS Foundation Trust, Gillingham, UK.

Applied Intelligence, Accenture, London, UK.

出版信息

Eur Urol. 2020 Dec;78(6):775-776. doi: 10.1016/j.eururo.2020.09.031. Epub 2020 Sep 17.

DOI:10.1016/j.eururo.2020.09.031
PMID:32994064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7498248/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic has generated large volumes of clinical data that can be an invaluable resource towards answering a number of important questions for this and future pandemics. Artificial intelligence can have an important role in analysing such data to identify populations at higher risk of COVID-19-related urological pathologies and to suggest treatments that block viral entry into cells by interrupting the angiotensin-converting enzyme 2-transmembrane serine protease 2 (ACE2-TMPRSS2) pathway.

摘要

2019 年冠状病毒病(COVID-19)大流行产生了大量的临床数据,这些数据对于回答这一流行病和未来流行病的许多重要问题是非常宝贵的资源。人工智能在分析这些数据以识别 COVID-19 相关泌尿系统疾病风险较高的人群以及通过阻断血管紧张素转换酶 2-跨膜丝氨酸蛋白酶 2(ACE2-TMPRSS2)途径来抑制病毒进入细胞的治疗方法方面可以发挥重要作用。

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2
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ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Serine Protease 2) Expression and Localization of SARS-CoV-2 Infection in the Human Heart.血管紧张素转换酶2(ACE2)和跨膜丝氨酸蛋白酶2(TMPRSS2)在人心脏中SARS-CoV-2感染的表达与定位
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本文引用的文献

1
A Global Survey on the Impact of COVID-19 on Urological Services.一项关于 COVID-19 对泌尿外科服务影响的全球调查。
Eur Urol. 2020 Aug;78(2):265-275. doi: 10.1016/j.eururo.2020.05.025. Epub 2020 May 26.
2
Expression of ACE2, the SARS-CoV-2 Receptor, and TMPRSS2 in Prostate Epithelial Cells.血管紧张素转换酶2(ACE2)、严重急性呼吸综合征冠状病毒2(SARS-CoV-2)受体及跨膜丝氨酸蛋白酶2(TMPRSS2)在前列腺上皮细胞中的表达
Eur Urol. 2020 Aug;78(2):296-298. doi: 10.1016/j.eururo.2020.04.065. Epub 2020 May 6.
3
Real-time tracking of self-reported symptoms to predict potential COVID-19.实时跟踪自我报告的症状以预测潜在的 COVID-19。
Nat Med. 2020 Jul;26(7):1037-1040. doi: 10.1038/s41591-020-0916-2. Epub 2020 May 11.
4
Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532).雄激素剥夺疗法治疗前列腺癌与 SARS-CoV-2 感染风险的关系:一项基于人群的研究(N=4532)。
Ann Oncol. 2020 Aug;31(8):1040-1045. doi: 10.1016/j.annonc.2020.04.479. Epub 2020 May 6.
5
European Association of Urology Guidelines Office Rapid Reaction Group: An Organisation-wide Collaborative Effort to Adapt the European Association of Urology Guidelines Recommendations to the Coronavirus Disease 2019 Era.欧洲泌尿外科学会指南办公室快速反应小组:全组织协作努力,使欧洲泌尿外科学会指南推荐适应 2019 年冠状病毒病时代。
Eur Urol. 2020 Jul;78(1):21-28. doi: 10.1016/j.eururo.2020.04.056. Epub 2020 Apr 27.
6
Using Artificial Intelligence to Detect COVID-19 and Community-acquired Pneumonia Based on Pulmonary CT: Evaluation of the Diagnostic Accuracy.基于肺部 CT 的人工智能检测 COVID-19 和社区获得性肺炎:诊断准确性评估。
Radiology. 2020 Aug;296(2):E65-E71. doi: 10.1148/radiol.2020200905. Epub 2020 Mar 19.
7
Baricitinib as potential treatment for 2019-nCoV acute respiratory disease.巴瑞替尼作为2019新型冠状病毒急性呼吸道疾病的潜在治疗方法。
Lancet. 2020 Feb 15;395(10223):e30-e31. doi: 10.1016/S0140-6736(20)30304-4. Epub 2020 Feb 4.
8
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak.基于 RNA 的宏基因组二代测序(mNGS)方法从 2019 年武汉暴发的两例肺炎个体病例中鉴定出一种新型人类冠状病毒。
Emerg Microbes Infect. 2020 Feb 5;9(1):313-319. doi: 10.1080/22221751.2020.1725399. eCollection 2020.