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常规基本代谢面板并非所有初次全关节置换术后患者所必需:降低成本的机会。

Routine Basic Metabolic Panels Are Not Needed in All Patients After Primary Total Joint Arthroplasty: An Opportunity for Cost Reduction.

机构信息

Department of Orthopaedic Surgery, The Johns Hopkins School of Medicine, Baltimore, MD.

出版信息

J Arthroplasty. 2021 Feb;36(2):462-466. doi: 10.1016/j.arth.2020.08.020. Epub 2020 Aug 14.

DOI:10.1016/j.arth.2020.08.020
PMID:32994110
Abstract

BACKGROUND

As the incidence of total joint arthroplasty (TJA) increases, identifying methods for cost reduction is essential. Basic metabolic panels (BMPs) are obtained routinely after TJA. We aimed at assessing the prevalence of intervention secondary to abnormal BMPs after primary TJA and at identifying predictors of the need for postoperative BMPs.

METHODS

We reviewed 802 cases (758 patients) of primary lower-extremity TJA performed from January 1 through December 31, 2018, at our tertiary care medical center. Patient characteristics, preoperative and postoperative BMPs, comorbidities, current medications, and in-hospital interventions were recorded. Age-adjusted Charlson Comorbidity Index (AA-CCI) values were calculated. Institutional costs of 1 BMP and of all BMPs not prompting intervention were calculated. We used multiple regression to identify independent predictors of in-hospital interventions secondary to abnormal postoperative BMPs.

RESULTS

Our institutional BMP cost was $36. A total of 1032 postoperative BMPs were ordered; 958 (93%) prompted no intervention. This equated to $34,488 of avoidable BMP costs. We identified 27 cases (3.4%) requiring intervention secondary to abnormal BMPs. Independent predictors of intervention were preoperative renal dysfunction (ie, abnormal creatinine or glomerular filtration rate <60 mL/min) (odds ratio [OR], 7.8; 95% confidence interval [CI], 2.8-22), number of current nephrotoxic medications (OR, 1.9; 95% CI, 1.3-2.9), and AA-CCI value (OR, 1.2; 95% CI, 1.0-1.5).

CONCLUSION

Routine postoperative BMPs are unwarranted for most patients undergoing primary TJA. Testing may be reserved for those with renal dysfunction, those taking multiple nephrotoxic medications, or those with a high AA-CCI value.

摘要

背景

随着全关节置换术(TJA)发病率的增加,确定降低成本的方法至关重要。TJA 后常规获得基本代谢物套餐(BMP)。我们旨在评估原发性 TJA 后因 BMP 异常而进行干预的发生率,并确定需要术后 BMP 的预测因素。

方法

我们回顾了 2018 年 1 月 1 日至 12 月 31 日在我们的三级医疗中心进行的 802 例(758 例患者)原发性下肢 TJA。记录患者特征、术前和术后 BMP、合并症、当前药物和住院干预。计算年龄调整 Charlson 合并症指数(AA-CCI)值。计算 1 个 BMP 和所有未提示干预的 BMP 的机构成本。我们使用多元回归分析来确定因术后 BMP 异常而导致住院干预的独立预测因素。

结果

我们的机构 BMP 成本为 36 美元。共开具了 1032 份术后 BMP,其中 958 份(93%)未提示干预。这相当于 34488 美元的可避免 BMP 成本。我们发现 27 例(3.4%)因 BMP 异常需要干预。干预的独立预测因素是术前肾功能障碍(即肌酐异常或肾小球滤过率<60 mL/min)(优势比 [OR],7.8;95%置信区间 [CI],2.8-22)、当前使用的肾毒性药物数量(OR,1.9;95%CI,1.3-2.9)和 AA-CCI 值(OR,1.2;95%CI,1.0-1.5)。

结论

对于大多数接受原发性 TJA 的患者,常规术后 BMP 是不必要的。对于肾功能障碍、服用多种肾毒性药物或 AA-CCI 值较高的患者,可保留检测。

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