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Postepy Dermatol Alergol. 2020 Aug;37(4):445-451. doi: 10.5114/ada.2020.98226. Epub 2020 Sep 2.
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Current challenges and future opportunities in patient-focused management of hereditary angioedema: A narrative review.遗传性血管性水肿以患者为中心管理中的当前挑战与未来机遇:一项叙述性综述
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The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update.国际血管性水肿学会(WAO)/欧洲变态反应和临床免疫学会(EAACI)遗传性血管性水肿管理指南——2021年修订与更新
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1
Idiopathic Angioedema: Current Challenges.特发性血管性水肿:当前面临的挑战
J Asthma Allergy. 2020 Apr 17;13:137-144. doi: 10.2147/JAA.S205709. eCollection 2020.
2
Hereditary Angioedema.遗传性血管性水肿
N Engl J Med. 2020 Mar 19;382(12):1136-1148. doi: 10.1056/NEJMra1808012.
3
Angioedema without urticaria: novel findings which must be measured in clinical setting.无荨麻疹性血管性水肿:必须在临床环境中测量的新发现。
Curr Opin Allergy Clin Immunol. 2020 Jun;20(3):253-260. doi: 10.1097/ACI.0000000000000633.
4
Hereditary angioedema in a single family with specific mutations in both plasminogen and SERPING1 genes.单一家庭中的遗传性血管性水肿,纤溶酶原和 SERPING1 基因均存在特定突变。
J Dtsch Dermatol Ges. 2020 Mar;18(3):215-223. doi: 10.1111/ddg.14036. Epub 2020 Feb 17.
5
ACE inhibitor-mediated angioedema.血管紧张素转换酶抑制剂相关性血管水肿。
Int Immunopharmacol. 2020 Jan;78:106081. doi: 10.1016/j.intimp.2019.106081. Epub 2019 Dec 10.
6
The International/Canadian Hereditary Angioedema Guideline.《国际/加拿大遗传性血管性水肿指南》
Allergy Asthma Clin Immunol. 2019 Nov 25;15:72. doi: 10.1186/s13223-019-0376-8. eCollection 2019.
7
Lanadelumab Injection Treatment For The Prevention Of Hereditary Angioedema (HAE): Design, Development And Place In Therapy.用于预防遗传性血管性水肿(HAE)的注射用拉那度单抗:设计、研发及治疗地位
Drug Des Devel Ther. 2019 Oct 22;13:3635-3646. doi: 10.2147/DDDT.S192475. eCollection 2019.
8
Hereditary angioedema: an update on causes, manifestations and treatment.遗传性血管性水肿:病因、表现及治疗的最新进展
Br J Hosp Med (Lond). 2019 Jul 2;80(7):391-398. doi: 10.12968/hmed.2019.80.7.391.
9
Hereditary angioedema cosegregating with a novel kininogen 1 gene mutation changing the N-terminal cleavage site of bradykinin.遗传性血管性水肿与一种新型激肽原1基因突变共分离,该突变改变了缓激肽的N端切割位点。
Allergy. 2019 Dec;74(12):2479-2481. doi: 10.1111/all.13869. Epub 2019 Jun 7.
10
Angiotensin II receptor blockers are safe in patients with prior angioedema related to angiotensin-converting enzyme inhibitors - a nationwide registry-based cohort study.血管紧张素 II 受体阻滞剂在既往与血管紧张素转换酶抑制剂相关血管性水肿的患者中是安全的 - 一项基于全国登记的队列研究。
J Intern Med. 2019 May;285(5):553-561. doi: 10.1111/joim.12867. Epub 2019 Jan 8.

血管性水肿。波兰皮肤病学会(PTD)和波兰变态反应学会(PTA)的多学科诊断与治疗建议。

Angioedema. Interdisciplinary diagnostic and therapeutic recommendations of the Polish Dermatological Society (PTD) and Polish Society of Allergology (PTA).

作者信息

Nowicki Roman J, Grubska-Suchanek Elżbieta, Porêbski Grzegorz, Kowalski Marek L, Jahnz-Różyk Karina, Matuszewski Tomasz, Rudnicka Lidia, Kulus Marek, Barañska-Rybak Wioletta, Czajkowski Rafał, Doniec Zbigniew, Kowalewski Cezary, Krêcisz Beata, Lange Magdalena, Narbutt Joanna, Olszewska Małgorzata, Sokołowska-Wojdyło Małgorzata, Szczerkowska-Dobosz Aneta, Śpiewak Radosław, Trzeciak Magdalena, Wilkowska Aleksandra

机构信息

Department of Dermatology, Venerology and Allergology, Medical University of Gdansk, Gdansk, Poland.

Department of Clinical and Environmental Allergology, Jagiellonian University, Clinical and Environmental Allergology Centre, University Hospital, Krakow, Poland.

出版信息

Postepy Dermatol Alergol. 2020 Aug;37(4):445-451. doi: 10.5114/ada.2020.98226. Epub 2020 Sep 2.

DOI:10.5114/ada.2020.98226
PMID:32994763
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7507159/
Abstract

Angioedema is a non-inflammatory oedema of the subcutaneous tissue and/or mucosal membranes. It most commonly coexists with urticaria wheals and is considered to be a deep form of urticaria. Less commonly, it occurs in isolation and can take two basic forms: acquired angioedema and hereditary angioedema. Currently, there are 4 defined types of acquired angioedema and 7 types of hereditary angioedema. Treatment of angioedema depends on its form and etiological factors. Especially the genetic form, i.e. hereditary angioedema, is a considerable challenge for medical specialists, particularly dermatologists and allergists.

摘要

血管性水肿是皮下组织和/或黏膜的非炎性水肿。它最常与荨麻疹风团同时存在,被认为是一种深部形式的荨麻疹。较少见的情况是,它单独出现,可呈现两种基本形式:获得性血管性水肿和遗传性血管性水肿。目前,有4种已明确的获得性血管性水肿类型和7种遗传性血管性水肿类型。血管性水肿的治疗取决于其形式和病因。特别是遗传形式,即遗传性血管性水肿,对医学专家,尤其是皮肤科医生和过敏症专科医生来说是一个相当大的挑战。