肝移植与衰老
Liver transplantation and aging.
作者信息
Mikulic Danko, Mrzljak Anna
机构信息
Department of Abdominal and Transplant Surgery, Merkur University Hospital, Zagreb 10000, Croatia.
Department of Medicine, Merkur University Hospital; School of Medicine, University of Zagreb, Zagreb 10000, Croatia.
出版信息
World J Transplant. 2020 Sep 18;10(9):256-266. doi: 10.5500/wjt.v10.i9.256.
Abstract
An increase in the average life expectancy, paralleled by a demographic shift in the population with end-stage liver disease lies behind the rising demand for liver transplantation (LT) among the elderly. Some of the most common indications for LT including hepatocellular carcinoma, alcohol-related liver disease, chronic hepatitis C and non-alcoholic fatty liver disease tend to affect older patients. Transplant professionals are faced with an increasing demand for LT among elderly patients in an age of organ shortage and it is important that risk and benefits are carefully weighed in order to achieve the optimum use of precious liver grafts.
摘要
平均预期寿命的增加，伴随着终末期肝病患者群体的人口结构变化，是老年人对肝移植（LT）需求上升的背后原因。LT的一些最常见适应症，包括肝细胞癌、酒精性肝病、慢性丙型肝炎和非酒精性脂肪性肝病，往往会影响老年患者。在器官短缺的时代，移植专业人员面临着老年患者对LT的需求不断增加的情况，为了实现珍贵肝脏移植物的最佳利用，仔细权衡风险和益处非常重要。
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