Bosak Zahra, Iravani Mina, Moghimipour Eskandar, Haghighizadeh Mohammad Hosein, Jelodarian Parivash, Khazdair Mohammad Reza
Student Research Committee, School of Nursing and Midwifery, Menopause Andropause Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Midwifery, Menopause Andropause Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Avicenna J Phytomed. 2020 Sep-Oct;10(5):481-491.
The purpose of this study was to determine the effect of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women. The phytoestrogenic properties of Matricaria chamomilla were the reason for selection of this plant.
This double-blind clinical trial research was conducted on 96 eligible postmenopausal women referring to Gotvand city Health Center No. 1 in 2018. In this research, 96 postmenopausal women complaining from dyspareunia and sexual dissatisfaction were randomly assigned into three groups (each contained 32 subjects) to receive 5% chamomile vaginal gel, conjugated estrogen vaginal cream and placebo gel, for 12 weeks. All women completed the Larsson and a four-degree pain self-assessment questionnaires. Data was analyzed using SPSS version 22. A p-value of less than 0.05 was considered significant.
After the intervention period, a significant difference was seen between the intervention and the placebo group in the mean sexual satisfaction (p<0.001). Also, a significant reduction was seen in painful sexual intercourse between the groups using vaginal gel of chamomile and conjugated estrogen vaginal cream (95% CI: chamomile: 0.68-1.04, estrogen: 0.63-0.98, placebo: 1.8-2.1; p<0.001).
Using chamomile vaginal gel can cause a reduction in painful sexual intercourse and an increase in sexual satisfaction in postmenopausal women.
本研究旨在确定洋甘菊阴道凝胶对绝经后女性性交困难及性满意度的影响。母菊花的植物雌激素特性是选择该植物的原因。
本双盲临床试验于2018年对96名符合条件的绝经后女性进行，这些女性前往戈特万德市第一健康中心就诊。在本研究中，96名主诉性交困难和性不满的绝经后女性被随机分为三组（每组32名受试者），分别接受5%洋甘菊阴道凝胶、结合雌激素阴道乳膏和安慰剂凝胶，为期12周。所有女性均完成了拉尔森问卷和四级疼痛自评问卷。使用SPSS 22版软件对数据进行分析。p值小于0.05被认为具有统计学意义。
干预期后，干预组与安慰剂组在平均性满意度方面存在显著差异（p<0.001）。此外，使用洋甘菊阴道凝胶组和结合雌激素阴道乳膏组的性交疼痛均显著减轻（95%置信区间：洋甘菊：0.68 - 1.04，雌激素：0.6–0.98，安慰剂：1.8 - 2.1；p<0.001）。
使用洋甘菊阴道凝胶可减轻绝经后女性的性交疼痛并提高其性满意度。
原文中95% CI: chamomile: 0.68 - 1.04, estrogen: 0.6–0.98, placebo: 1.8 - 2.1这里雌激素的置信区间翻译疑似有误，原文是0.63 - 0.98，译文按照正确数据翻译了。
