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抗栓治疗对慢性硬膜下血肿钻孔引流术后急性硬膜下血肿发生的影响。

Effect of Antithrombotic Therapy on Development of Acute Subdural Hematoma After Burr Hole Drainage of Chronic Subdural Hematoma.

作者信息

Yuksel Mehmet Onur, Cevik Serdar, Erdogan Baris, Tunckale Tamer, Katar Salim, Isik Semra, Caliskan Tezcan, Evran Sevket

机构信息

Bahcelievler Nisa Hospital, Department of Neurosurgery, Istanbul, Turkey.

出版信息

Turk Neurosurg. 2020;30(5):758-762. doi: 10.5137/1019-5149.JTN.30423-20.3.

Abstract

AIM

To evaluate the relationship between the time from cessation of anticoagulant/antiplatelet medication to surgery and risk of postoperative acute subdural hematoma (ASDH) after burr hole drainage of chronic subdural hematoma (CSDH).

MATERIAL AND METHODS

A retrospective study of patients who underwent burr hole drainage of CSDH between December 2014 and December 2019 was performed. Demographic and clinical data regarding age, gender, medication (antithrombotic therapy), smoking, daily alcohol consumption, history of head trauma, presenting symptoms, and neurological examination were collected from the medical records. Patients were divided into 3 groups based on time from referral to surgery: < 24 hours, 24?72 hours, and > 72 hours.

RESULTS

One hundred seventeen patients underwent burr hole drainage of CSDH during the 5-year study period. Seventy-two patients were male (61.5%) and 45 were female (38.5%). Mean age was 70.5 ± 7.2 years. Postoperative ASDH occurred in 2 of the 32 patients (6.3%) who were not taking antithrombotic medication and 6 of the 85 patients (7.1%) who were taking antithrombotic medication. The difference was not significant (p=0.797).

CONCLUSION

The risk of ASDH after burr hole drainage of CSDH was not affected by antithrombotic medication. Although the literature suggests that antiplatelet and anticoagulant drugs to be discontinued between 5 and 7 days before surgery, our results showed that acute hemorrhage was not detected in any patient who underwent surgery more than 72 hours after referral.

摘要

目的

评估慢性硬膜下血肿(CSDH)钻孔引流术后,从停用抗凝/抗血小板药物至手术的时间与术后急性硬膜下血肿(ASDH)风险之间的关系。

材料与方法

对2014年12月至2019年12月期间接受CSDH钻孔引流术的患者进行回顾性研究。从病历中收集有关年龄、性别、用药情况(抗血栓治疗)、吸烟、每日饮酒量、头部外伤史、出现的症状以及神经学检查的人口统计学和临床数据。根据从转诊至手术的时间将患者分为3组:<24小时、24 - 72小时和>72小时。

结果

在5年的研究期间,117例患者接受了CSDH钻孔引流术。72例为男性(61.5%),45例为女性(38.5%)。平均年龄为70.5±7.2岁。未服用抗血栓药物的32例患者中有2例(6.3%)发生术后ASDH,服用抗血栓药物的85例患者中有6例(7.1%)发生术后ASDH。差异无统计学意义(p = 0.797)。

结论

CSDH钻孔引流术后ASDH的风险不受抗血栓药物的影响。尽管文献表明抗血小板和抗凝药物应在手术前5至7天停用,但我们的结果显示,在转诊后超过72小时接受手术的患者中未发现急性出血情况。

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