青少年类风湿性关节炎患者滑膜切除术与非滑膜切除术的比较。一项为期24个月的对照研究。

Comparison of synovectomy and no synovectomy in patients with juvenile rheumatoid arthritis. A 24-month controlled study.

作者信息

Kvien T K, Pahle J A, Høyeraal H M, Sandstad B

出版信息

Scand J Rheumatol. 1987;16(2):81-91. doi: 10.3109/03009748709102912.

Abstract

Thirty patients with pauciarticular or polyarticular juvenile rheumatoid arthritis entered a randomized, 24-month, parallel trial of synovectomy (n = 15) versus no synovectomy (n = 15). The joints studied were 18 wrists, 8 ankles and 4 knees. The synovectomies were performed as radically as possible. Joint motion was slightly decreased in the operated joints, especially for passive movements during the first 6 months following surgery. Swelling and disease activity of the joints studied as well as subjective evaluation of joint pain improved in the synovectomy group compared with the non-synovectomy group. This improvement seemed to continue for at least 2 years.

摘要

30例少关节型或多关节型幼年类风湿关节炎患者进入了一项为期24个月的随机平行试验，比较滑膜切除术（n = 15）与非滑膜切除术（n = 15）的效果。研究的关节包括18个腕关节、8个踝关节和4个膝关节。滑膜切除术尽可能彻底地进行。手术关节的关节活动度略有下降，尤其是在术后前6个月的被动活动中。与非滑膜切除术组相比，滑膜切除术组研究关节的肿胀和疾病活动度以及关节疼痛的主观评估均有所改善。这种改善似乎至少持续了2年。