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青少年类风湿关节炎滑膜切除术的远期疗效

Late results of synovectomy in juvenile rheumatoid arthritis.

作者信息

Jacobsen S T, Levinson J E, Crawford A H

出版信息

J Bone Joint Surg Am. 1985 Jan;67(1):8-15.

PMID:3968106
Abstract

We reviewed the records of 251 patients whose cases were diagnosed between 1958 and 1978 at the Children's Hospital Medical Center Special Treatment Center for Juvenile Arthritis. We used a computerized system that included retrieval of data on range of motion, pain, joint swelling, functional capacity, and radiographic changes at each six-month visit over the years that the patient was followed. For the patients who were operated on, the radiographic information was evaluated preoperatively and at the last radiographic follow-up (average, six years after operation). The data bank contained postoperative radiographic information for thirty-two of the joints that had been operated on. We reviewed the late results of forty-one synovectomies in thirty children. The data included range of motion, swelling, and pain before operation, at one and two years after operation, and at an average of 7.1 years of follow-up. There were few if any benefits from the operation with reference to pain or improvement of range of motion, but it did seem to provide permanent relief of the joint swelling. Furthermore, radiographic deterioration seemed to continue in the joints that had been operated on if they already had radiographic changes at the time of operation (late synovectomy). In the joints without radiographic changes at the time of operation (early synovectomy), there seemed to be a continuation of deterioration in those affected by polyarticular disease, while the changes were less pronounced in those affected by pauciarticular disease. We undertook this study with a positive attitude toward synovectomy in the treatment of juvenile rheumatoid arthritis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们回顾了1958年至1978年间在儿童医院医疗中心青少年关节炎特殊治疗中心确诊的251例患者的病历。我们使用了一个计算机系统,该系统包括检索患者随访多年来每次六个月就诊时的活动范围、疼痛、关节肿胀、功能能力和影像学变化的数据。对于接受手术的患者,术前和最后一次影像学随访(平均术后六年)时对影像学信息进行评估。数据库包含了32个接受手术关节的术后影像学信息。我们回顾了30名儿童41次滑膜切除术的后期结果。数据包括手术前、手术后1年和2年以及平均随访7.1年时的活动范围、肿胀和疼痛情况。手术在疼痛或活动范围改善方面几乎没有益处,但似乎确实能使关节肿胀得到永久性缓解。此外,如果手术时关节已经有影像学改变(晚期滑膜切除术),则手术后关节的影像学恶化似乎会持续。在手术时无影像学改变的关节(早期滑膜切除术)中,多关节疾病患者的关节恶化似乎会持续,而少关节疾病患者的变化则不太明显。我们对滑膜切除术治疗青少年类风湿关节炎持积极态度开展了这项研究。(摘要截短至250字)

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Late results of synovectomy in juvenile rheumatoid arthritis.青少年类风湿关节炎滑膜切除术的远期疗效
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Results of synovectomy in children with rheumatoid arthritis.类风湿关节炎患儿滑膜切除术的结果。
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