Department of Psychosomatic Medicine, Kansai Medical University, Hirakata, Japan.
Department of Palliative Medicine, National Cancer Center Hospital, Chuo-ku, Japan.
J Palliat Med. 2021 May;24(5):697-704. doi: 10.1089/jpm.2020.0371. Epub 2020 Sep 30.
Despite the suggestion of a relationship between development or progression of myofascial pain syndrome (MPS) and psychological stress, few studies have reported its proportion or association with treatment efficacy. We aimed to investigate the proportion of MPS with psychological stress among cancer patients and to compare the efficacy of trigger point injection (TPI) in the same patients with/without psychological stress. This was a prospective observational study. Participants were 205 patients with cancer who received TPIs for MPS at a hospital in Japan. The proportion of patients with MPS and psychological stress was 0.57 (95% confidence interval [CI] 0.50-0.64). The TPI efficacy rate at seven days after treatment was 0.55 (95% CI 0.46-0.64) for patients with MPS and psychological stress and 0.82 (95% CI 0.74-0.90) for their counterparts without psychological stress ( < 0.004). The odds ratio for TPI efficacy seven days after treatment with psychological stress versus without psychological stress was 0.25 (95% CI 0.13-0.49). MPS was a clinical symptom of psychosomatic disorder in approximately half of our patients. The TPI efficacy for patients with MPS who had psychological stress was lower than for their counterparts without psychological stress. Trial registration: UMIN000041210. Registered 27 July 2020 (retrospectively registered).
尽管有研究表明肌筋膜疼痛综合征（MPS）的发展或进展与心理压力之间存在关系，但很少有研究报告其比例或与治疗效果的关系。我们旨在调查癌症患者中存在心理压力的 MPS 比例，并比较在有/无心理压力的相同患者中，触发点注射（TPI）的疗效。这是一项前瞻性观察性研究。参与者为 205 名在日本一家医院接受 MPS 触发点注射治疗的癌症患者。患有 MPS 和心理压力的患者比例为 0.57（95%置信区间[CI]0.50-0.64）。治疗后 7 天时 TPI 的疗效率为患有 MPS 和心理压力的患者为 0.55（95%CI0.46-0.64），而无心理压力的患者为 0.82（95%CI0.74-0.90）（ < 0.004）。治疗后 7 天时 TPI 疗效的心理压力与无心理压力的比值为 0.25（95%CI0.13-0.49）。MPS 是我们大约一半患者心身障碍的临床症状。有心理压力的 MPS 患者的 TPI 疗效低于无心理压力的患者。试验注册：UMIN000041210。2020 年 7 月 27 日注册（回顾性注册）。
