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一种用于确定与疾病严重程度呈负相关的新甲襞反向超声指数的诊断截断值的建议。

A Proposal for Determining a Diagnostic Cutoff Value of a New Ultrasonographic Index of Retronychia Inversely Correlating with Disease Severity.

出版信息

J Am Podiatr Med Assoc. 2020 Jul 1;110(4). doi: 10.7547/17-167.

Abstract

BACKGROUND

Ultrasonography has demonstrated a shortening of the distance between the origin of the nail plate and the base of the distal phalanx in retronychia. The aim of this study was to analyze the clinical and ultrasonographic features of retronychia.

METHODS

We evaluated the clinical findings in 18 patients with retronychia, along with the ratio of ultrasonographic distance a, extending between the nail plate origin and the base of the distal phalanx, to distance b, perpendicular to distance a, extending between the nail plate origin and the upper margin of the distal phalanx.

RESULTS

Retronychia was present in 26 nails. The mean ± SD distance a was 7.66 ± 1.64 mm and distance b was 3.56 ± 1.95 mm. The mean ± SD a/b ratio was 2.59 ± 1.11. There was a significant inverse correlation between a/b ratio and clinical severity (Pearson correlation = -0.668; P < .001). The cutoff value of this ratio was 3.319, with specificity of 90% and sensitivity of 69%.

CONCLUSIONS

The ratio of distance a/distance b and the cutoff value of this ratio may help in making the diagnosis, in objectively determining the disease severity, and in selecting a patient-specific treatment approach.

摘要

背景

超声检查显示甲襞根部到远侧甲床基底之间的距离缩短与反甲有关。本研究旨在分析反甲的临床和超声特征。

方法

我们评估了 18 例反甲患者的临床发现,以及超声测量的甲襞根部到远侧甲床基底之间的距离 a 与甲襞根部到远侧甲床上缘之间的垂直距离 b 之间的比值。

结果

26 个指甲存在反甲。a 距离的平均值 ± 标准差为 7.66 ± 1.64mm,b 距离的平均值 ± 标准差为 3.56 ± 1.95mm。a/b 比值的平均值 ± 标准差为 2.59 ± 1.11。a/b 比值与临床严重程度呈显著负相关(皮尔逊相关系数=-0.668;P<0.001)。该比值的截断值为 3.319,特异性为 90%,敏感性为 69%。

结论

距离 a/距离 b 的比值及其截断值有助于诊断,客观地确定疾病严重程度,并为患者选择个体化的治疗方法。

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