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Insights image for "The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling.".

作者信息

Sodhi Chhinder P, Wipf Peter, Yamaguchi Yukihiro, Fulton William B, Kovler Mark, Niño Diego F, Zhou Qinjie, Banfield Emilyn, Werts Adam D, Ladd Mitchell R, Buck Rachael H, Goehring Karen C, Prindle Thomas, Wang Sanxia, Jia Hongpeng, Lu Peng, Hackam David J

机构信息

Division of General Pediatric Surgery, Johns Hopkins University and Johns Hopkins Children's Center, Baltimore, MD, 21287, USA.

Department of Surgery, Johns Hopkins University and Johns Hopkins Children's Center, Baltimore, MD, 21287, USA.

出版信息

Pediatr Res. 2021 Jan;89(1):248. doi: 10.1038/s41390-020-01184-w. Epub 2020 Sep 30.

DOI:10.1038/s41390-020-01184-w
PMID:32998155
Abstract
摘要

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Insights image for "The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling.".关于“The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling.”的见解图像。
Pediatr Res. 2021 Jan;89(1):248. doi: 10.1038/s41390-020-01184-w. Epub 2020 Sep 30.
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The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling.人乳寡糖 2'-岩藻糖基乳糖和 6'-唾液酸乳糖通过抑制 Toll 样受体 4 信号通路来预防坏死性小肠结肠炎的发生。
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Major human milk oligosaccharides are absorbed into the systemic circulation after oral administration in rats.主要的人乳寡糖在大鼠口服给药后被吸收进入体循环。
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Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis.肠道上皮屏障功能与坏死性小肠结肠炎
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