Yang Fangfang, Wu Mao, Peng Yumeng, Dong Xiaoyan, Ge Yumei
Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
Ear Nose Throat J. 2022 Jul;101(6):NP266-NP269. doi: 10.1177/0145561320964267. Epub 2020 Oct 1.
Parotid gland tuberculosis constantly results in unnecessary medical examinations and surgery because of its similarities in the presentation to neoplasms of the parotid gland. Although parotid gland involvement is extremely rare even in tuberculosis-endemic countries, accurate diagnosis of this clinical entity is of great significance because tuberculous parotitis can be successfully treated medically without surgical therapy. Fine needle aspiration cytology (FNAC) and molecular identification of the parotid swellings are efficient in making a rapid diagnosis. Herein, we report an early misdiagnosis of malignancy from a renal transplantation patient on long-term immunologic inhibitor therapy, who ultimately proved to have tuberculosis of the parotid gland by FNAC and molecular identification. The aim of this study is to describe and analyze the etiologic characteristics, epidemiology, clinical presentations, diagnostic methods, histopathologic findings, and pathogenic mechanisms of these rare infections.
腮腺结核因其临床表现与腮腺肿瘤相似，常常导致不必要的医学检查和手术。尽管即使在结核病流行国家，腮腺受累也极为罕见，但准确诊断这一临床实体具有重要意义，因为结核性腮腺炎可通过药物治疗成功治愈，无需手术治疗。细针穿刺细胞学检查（FNAC）和腮腺肿块的分子鉴定有助于快速诊断。在此，我们报告一例长期接受免疫抑制剂治疗的肾移植患者，其腮腺肿物最初被误诊为恶性肿瘤，最终通过FNAC和分子鉴定确诊为腮腺结核。本研究的目的是描述和分析这些罕见感染的病因特征、流行病学、临床表现、诊断方法、组织病理学发现及发病机制。
