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Descemet膜剥脱自动内皮角膜移植术后界面液体的晚期自发吸收

Late Spontaneous Reabsorption of Interface Fluid after Descemet's Stripping Automated Endothelial Keratoplasty Surgery.

作者信息

Romanazzi Filippo, Morano Anna, Caccavale Antonio

机构信息

Department of Ophthalmology, Abbiategrasso Hospital, ASST Ovest Milanese, Abbiategrasso, Italy.

出版信息

Case Rep Ophthalmol. 2020 Aug 6;11(2):423-429. doi: 10.1159/000509262. eCollection 2020 May-Aug.

DOI:10.1159/000509262
PMID:32999671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7506283/
Abstract

An 80-year-old male was referred to our hospital for chronic bullous keratopathy in the right eye. Ten years before, he was affected by an attack of primary acute angle closure glaucoma in high hyperopia and Fuchs' endothelial dystrophy. A bilateral iridotomy was performed. Thereafter, the patient developed an endothelial decompensation in the left eye, and, in another hospital, he underwent an open-sky combined cataract extraction and penetrating keratoplasty. Our surgical approach for the right eye consisted of phacoemulsification and, after 1 month, a Descemet's stripping automated endothelial keratoplasty (DSAEK). After the procedure, an interface fluid was suspected, and an anterior segment optical coherence tomography (OCT) confirmed it. The graft was well centered but thickened, showing no movement in the anterior chamber, adherent to the periphery of the recipient cornea but with a pool of fluid in the center. Seven days postoperatively, an anterior segment OCT showed initial signs of reabsorption of the fluid. On day 45, the graft was adherent with normal thickness and the interface fluid had completely disappeared. The corneal stroma was clear, but a faint interface opacity appeared and is still present. We obtained a good surgical result and best corrected visual acuity was 7/10 at postoperative month 4. No further surgical procedures are scheduled.

摘要

一名80岁男性因右眼慢性大疱性角膜病变被转诊至我院。10年前,他患有原发性急性闭角型青光眼发作,伴有高度远视和富克斯内皮营养不良。进行了双侧虹膜切开术。此后,患者左眼出现内皮失代偿,并在另一家医院接受了开放式联合白内障摘除和穿透性角膜移植术。我们对右眼的手术方法包括超声乳化术,1个月后进行了Descemet膜剥脱自动内皮角膜移植术(DSAEK)。术后怀疑有界面液,前段光学相干断层扫描(OCT)证实了这一点。移植物居中良好但增厚,在前房内无移动,与受体角膜周边粘连,但中央有一液池。术后7天,前段OCT显示液体积聚开始出现吸收迹象。在第45天,移植物粘连,厚度正常,界面液已完全消失。角膜基质清晰,但出现了淡淡的界面混浊,目前仍然存在。我们获得了良好的手术效果,术后4个月最佳矫正视力为7/10。未安排进一步的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/50a2e6ac5699/cop-0011-0423-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/3c60f70f4484/cop-0011-0423-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/9cc7295fa450/cop-0011-0423-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/6c98ed5b5564/cop-0011-0423-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/50a2e6ac5699/cop-0011-0423-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/3c60f70f4484/cop-0011-0423-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/9cc7295fa450/cop-0011-0423-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/6c98ed5b5564/cop-0011-0423-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544a/7506283/50a2e6ac5699/cop-0011-0423-g04.jpg

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本文引用的文献

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Factors Associated With Graft Detachment After Primary Descemet Stripping Automated Endothelial Keratoplasty.原发性后弹力层剥除自动角膜内皮移植术后移植物脱离的相关因素
Cornea. 2017 Mar;36(3):265-268. doi: 10.1097/ICO.0000000000001123.
2
Intraoperative Interface Fluid Dynamics and Clinical Outcomes for Intraoperative Optical Coherence Tomography-Assisted Descemet Stripping Automated Endothelial Keratoplasty From the PIONEER Study.先锋研究中术中光学相干断层扫描辅助的后弹力层剥除自动角膜内皮移植术的术中界面流体动力学及临床结果
Am J Ophthalmol. 2017 Jan;173:16-22. doi: 10.1016/j.ajo.2016.09.028. Epub 2016 Oct 1.
3
Graft Detachment Rate in DSEK/DSAEK After Same-Day Complete Air Removal.
当日完全排气后DSEK/DSAEK中的植片脱离率
Cornea. 2015 Nov;34(11):1358-61. doi: 10.1097/ICO.0000000000000617.
4
Textural interface opacity after Descemet-stripping automated endothelial keratoplasty.后弹力层剥除自动角膜内皮移植术后的组织界面混浊
J Cataract Refract Surg. 2014 Sep;40(9):1514-20. doi: 10.1016/j.jcrs.2013.12.020.
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Association between transient interface fluid on intraoperative OCT and textural interface opacity after DSAEK surgery in the PIONEER study.PIONEER 研究中术中 OCT 上的瞬态界面液与 DSAEK 手术后的纹理状界面不透明之间的关联。
Cornea. 2014 Sep;33(9):887-92. doi: 10.1097/ICO.0000000000000209.
6
Clinicopathologic correlation of textural interface opacities in descemet stripping automated endothelial keratoplasty: a case study.Descemet 撕囊自动化内皮角膜移植术中纹理界面混浊的临床病理相关性:病例研究。
Cornea. 2014 Mar;33(3):306-9. doi: 10.1097/ICO.0000000000000057.
7
Persistent corneal opacity after descemet stripping automated endothelial keratoplasty suggesting inert material deposits into the interface.Descemet 撕囊自动化内皮角膜移植术后持续性角膜混浊,提示界面内惰性物质沉积。
Cornea. 2013 Nov;32(11):1512-3. doi: 10.1097/ICO.0b013e3182a1bc49.
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Cornea. 2013 May;32(5):e54-9. doi: 10.1097/ICO.0b013e31826429d5.
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