Platonova A L, Rogacheva T A, Isaeva E I, Rovnova Z I
Vopr Virusol. 1987 Mar-Apr;32(2):159-63.
Two heterogeneous antigens, Forssman antigen and an antigen similar to human group A antigen, were detected by enzyme-immunoassay in cells of normal chick embryo CAMN and MDCK culture (dog kidney). Both these antigens were associated with purified influenza B virus preparations reproduced in these cultures since the variants under study actively reacted with antibodies both to Forssman antigen and to human A antigen. Serological differences between the variants grown in different cell systems were due to the presence in their composition of the species-specific cell component typical either of chick embryo tissues or MDCK cultures, since the viruses of chicken origin contained the specific cell antigen CAMN, whereas the same viruses grown in MDCK did not contain it but had the specific activity for dog kidney cells. The virus-specific activity of the variants under study showed no significant differences in relation to host cells.
通过酶免疫测定法在正常鸡胚CAMN细胞和MDCK培养物（犬肾）中检测到两种异质性抗原，即福斯曼抗原和一种类似于人类A组抗原的抗原。这两种抗原都与在这些培养物中繁殖的纯化乙型流感病毒制剂相关，因为所研究的病毒变体与针对福斯曼抗原和人类A抗原的抗体都能发生积极反应。在不同细胞系统中生长的病毒变体之间的血清学差异是由于它们的组成中存在典型的鸡胚组织或MDCK培养物的物种特异性细胞成分，因为鸡源病毒含有特异性细胞抗原CAMN，而在MDCK中生长的相同病毒则不含有该抗原，但对犬肾细胞具有特异性活性。所研究的病毒变体的病毒特异性活性在与宿主细胞的关系上没有显示出显著差异。
