Sundar S
Acta Cardiol. 1987;42(2):135-9.
Plasma 6-Keto-Prostaglandin F1 alpha (6-Keto PG F1 alpha; stable hydrolysis product of prostacyclin) levels in 24 patients with essential hypertension and 15 age and sex matched healthy controls were studied. 6-Keto PG F1 alpha levels were measured in extracted plasma by radioimmunoassay using a commercial kit. The 6-Keto PG F1 alpha levels were significantly (P less than 0.001) higher in hypertensive patients as compared to controls. The raised levels of plasma 6-Keto PG F1 alpha in hypertensive patients may be an adaptive response of blood vessels to increased blood pressure.
对24例原发性高血压患者及15例年龄和性别匹配的健康对照者的血浆6-酮-前列腺素F1α（6-Keto PG F1α；前列环素的稳定水解产物）水平进行了研究。使用商用试剂盒通过放射免疫分析法测定提取血浆中的6-Keto PG F1α水平。与对照组相比，高血压患者的6-Keto PG F1α水平显著更高（P<0.001）。高血压患者血浆6-Keto PG F1α水平升高可能是血管对血压升高的一种适应性反应。
