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宫腔镜子宫肌瘤切除术后出现癫痫发作的严重低钠血症及确诊的轻度脑水肿:一例病例报告。

Severe hyponatremia with seizures and confirmed mild brain edema by hysteroscopic myomectomy: a case report.

作者信息

Okazaki Haruko, Miura Norikazu, Kashima Yuki, Miyashita Ryoichi, Oe Katsunori, Kawakami Keiko, Ishikawa Tetsuya, Masui Kenichi

机构信息

Department of Anesthesiology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8666, Japan.

Department of Intensive Care Medicine, Showa University School of Medicine, Tokyo, 142-8666, Japan.

出版信息

JA Clin Rep. 2020 Oct 1;6(1):74. doi: 10.1186/s40981-020-00381-0.

Abstract

BACKGROUND

Hyponatremia can be developed during hysteroscopic surgery with electrolyte-free irrigation fluid. We experienced severe hyponatremia with postoperative seizures and confirmed mild brain edema.

CASE PRESENTATION

A quadragenarian female patient underwent a 2-h hysteroscopic myomectomy with electrolyte-free fluid for uterine distension under general anesthesia. Plasma sodium level of 84.1 mmol/L 100 min after the start of surgery indicated excessive absorption of the irrigation fluid. Acute severe hyponatremia was diagnosed with significant edema in the conjunctiva, lip, and extremities. She was treated with a continuous infusion of hypertonic saline. However, seizures and cerebral edema developed 7 h later. The patient recovered without neurological deficits at postoperative day 2.

CONCLUSION

The electrolyte-free irrigation fluid can be absorbed rapidly during hysteroscopic surgery. Its interruption with hyponatremia should be considered against prolonged surgery. Especially under general anesthesia, caution should be exercised because the typical symptoms of hyponatremia such as nausea and confusion are blinded.

摘要

背景

在使用无电解质灌洗液的宫腔镜手术过程中可能会发生低钠血症。我们遇到了伴有术后癫痫发作的严重低钠血症,并证实存在轻度脑水肿。

病例报告

一名四十多岁的女性患者在全身麻醉下接受了为期2小时的宫腔镜子宫肌瘤切除术,术中使用无电解质液体进行子宫扩张。手术开始100分钟后血浆钠水平为84.1 mmol/L,表明灌洗液吸收过多。诊断为急性严重低钠血症,结膜、嘴唇和四肢出现明显水肿。她接受了高渗盐水持续输注治疗。然而,7小时后出现了癫痫发作和脑水肿。患者在术后第2天康复,无神经功能缺损。

结论

无电解质灌洗液在宫腔镜手术期间可迅速吸收。对于长时间手术,应考虑其与低钠血症的关联并加以预防。特别是在全身麻醉下,应格外小心,因为低钠血症的典型症状如恶心和意识模糊可能会被掩盖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ea0/7530158/0f09181468d9/40981_2020_381_Fig1_HTML.jpg

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