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多管齐下的行为干预措施可显著减少大泌尿外科手术后阿片类药物的处方。

Large reduction in opioid prescribing by a multipronged behavioral intervention after major urologic surgery.

机构信息

Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Center for Research on Health Care, University of Pittsburgh, Pittsburgh, Pennsylvania.

出版信息

Cancer. 2021 Jan 15;127(2):257-265. doi: 10.1002/cncr.33200. Epub 2020 Oct 1.

Abstract

BACKGROUND

Surgeons play a pivotal role in combating the opioid crisis that currently grips the United States. Changing surgeon behavior is difficult, and the degree to which behavioral science can steer surgeons toward decreased opioid prescribing is unclear.

METHODS

This was a single-institution, single-arm, pre- and postintervention study examining the prescribing of opioids by urologists for adult patients undergoing prostatectomy or nephrectomy. The primary outcome was the quantity of opioids prescribed in oral morphine equivalents (OMEs) after hospital discharge. The primary exposure was a multipronged behavioral intervention designed to decrease opioid prescribing. The intervention had 3 components: 1) formal education, 2) individual audit feedback, and 3) peer comparison performance feedback. There were 3 phases to the study: a pre-intervention phase, an intervention phase, and a washout phase.

RESULTS

Three hundred eighty-two patients underwent prostatectomy, and 306 patients underwent nephrectomy. The median OMEs decreased from 195 to 19 in the prostatectomy patients and from 200 to 0 in the nephrectomy patients (P < .05 for both). The median OMEs prescribed did not increase during the washout phase. Prostatectomy patients discharged with opioids had higher levels of anxiety than patients discharged without opioids (P < .05). Otherwise, prostatectomy and nephrectomy patients discharged with and without opioids did not differ in their perception of postoperative pain management, activity levels, psychiatric symptoms, or somatic symptoms (P > .05 for all).

CONCLUSIONS

Implementing a multipronged behavioral intervention significantly reduced opioid prescribing for patients undergoing prostatectomy or nephrectomy without compromising patient-reported outcomes.

摘要

背景

外科医生在美国目前面临的阿片类药物危机中发挥着关键作用。改变外科医生的行为是困难的,行为科学在多大程度上可以引导外科医生减少阿片类药物的处方还不清楚。

方法

这是一项单机构、单臂、干预前后研究,检查泌尿科医生为接受前列腺切除术或肾切除术的成年患者开具阿片类药物的处方情况。主要结果是出院后口服吗啡当量(OMEs)中开具的阿片类药物数量。主要暴露是一种多管齐下的行为干预措施,旨在减少阿片类药物的处方。该干预措施有 3 个组成部分:1)正规教育,2)个体审核反馈,3)同行比较绩效反馈。研究分为 3 个阶段:预干预阶段、干预阶段和洗脱阶段。

结果

382 名患者接受了前列腺切除术,306 名患者接受了肾切除术。前列腺切除术患者的 OMEs 中位数从 195 降至 19,肾切除术患者的 OMEs 中位数从 200 降至 0(两者均 P <.05)。在洗脱阶段,处方 OMEs 中位数没有增加。接受阿片类药物出院的前列腺切除术患者比没有接受阿片类药物出院的患者焦虑程度更高(P <.05)。否则,接受和不接受阿片类药物出院的前列腺切除术和肾切除术患者在术后疼痛管理、活动水平、精神症状或躯体症状方面没有差异(P >.05)。

结论

实施多管齐下的行为干预措施显著减少了前列腺切除术或肾切除术患者的阿片类药物处方,而不影响患者报告的结果。

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