Department of Medical Sciences, Uppsala University, Sweden.
Department of Neuroscience, Uppsala University, Sweden.
Pediatr Pulmonol. 2020 Dec;55(12):3509-3516. doi: 10.1002/ppul.25104. Epub 2020 Oct 20.
To study the prevalence of exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) in adolescent athletes.
All adolescents (n = 549) attending first year at a sports high school in 2016 and 2017, were invited to answer a questionnaire on respiratory symptoms. The 367 responding participants were divided into two groups based on whether they reported exercise-induced dyspnea (dyspnea group) or not (nondyspnea group). Randomly selected participants in each group were invited to undergo two standardized exercise tests, an EIB test and a continuous laryngoscopy exercise (CLE) test, to investigate EILO.
In total, 98 participants completed an EIB test, 75 of whom also completed a CLE test. Positive EIB tests: eight of 41 in the dyspnea group and 16 of 57 in the nondyspnea group. Positive CLE tests: 5 of 34 in the dyspnea group and three of 41 in the nondyspnea group. The estimated prevalence of EIB was 23.1% (95% confidence interval [CI]: 14.5-33.8) and of EILO 8.1% (95% CI: 2.5-18.5) in the whole study population. No differences in prevalence of EIB or EILO were found between the dyspnea and the nondyspnea groups.
EIB was highly prevalent in this cohort of adolescent athletes. EILO was less prevalent, but represents an important differential diagnosis to EIB. Self-reported exercise-induced dyspnea is a weak indicator for both EIB and EILO and standardized testing should be provided.
研究青少年运动员运动性支气管收缩(EIB)和运动性喉阻塞(EILO)的患病率。
2016 年和 2017 年,所有参加体育高中一年级的青少年(n=549)均被邀请回答一份关于呼吸系统症状的问卷。根据是否报告运动性呼吸困难(呼吸困难组)或不报告(非呼吸困难组),对 367 名应答参与者进行分组。随机选择每组的参与者进行两项标准化运动测试,即 EIB 测试和连续喉镜运动(CLE)测试,以调查 EILO。
共有 98 名参与者完成了 EIB 测试,其中 75 名还完成了 CLE 测试。EIB 测试阳性:呼吸困难组 41 名中的 8 名,非呼吸困难组 57 名中的 16 名。CLE 测试阳性:呼吸困难组 34 名中的 5 名,非呼吸困难组 41 名中的 3 名。EIB 的估计患病率为 23.1%(95%置信区间[CI]:14.5-33.8),EILO 的患病率为 8.1%(95%CI:2.5-18.5)。在整个研究人群中,呼吸困难组和非呼吸困难组之间 EIB 和 EILO 的患病率没有差异。
在该队列的青少年运动员中,EIB 高度流行。EILO 的患病率较低,但代表 EIB 的重要鉴别诊断。自我报告的运动性呼吸困难是 EIB 和 EILO 的一个弱指标,应提供标准化测试。