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A型主动脉夹层——超过 50 年的经验:JACC 的历史突破透视。

Type A Aortic Dissection-Experience Over 5 Decades: JACC Historical Breakthroughs in Perspective.

机构信息

Department of Cardiothoracic Surgery, Stanford University, Stanford, California.

Department of Epidemiology and Population Health, Stanford University, Stanford, California.

出版信息

J Am Coll Cardiol. 2020 Oct 6;76(14):1703-1713. doi: 10.1016/j.jacc.2020.07.061.

Abstract

The Stanford classification of aortic dissection was described in 1970. The classification proposed that type A aortic dissection should be surgically repaired immediately, whereas type B aortic dissection can be treated medically. Since then, diagnostic tools and management of acute type A aortic dissection (ATAAD) have undergone substantial evolution. This paper evaluated historical changes of ATAAD repair at Stanford University since the establishment of the aortic dissection classification 50 years ago. The surgical approaches to the proximal and distal extent of the aorta, cerebral perfusion methods, and cannulation strategies were reviewed. Additional analyses using patients who underwent ATAAD repair at Stanford University from 1967 through December 2019 were performed to further illustrate the Stanford experience in the management of ATAAD. While technical complexity increased over time, post-operative survival continued to improve. Further investigation is warranted to delineate factors associated with the improved outcomes observed in this study.

摘要

斯坦福大学的主动脉夹层分类法于 1970 年提出。该分类法建议立即对 A 型主动脉夹层进行手术修复,而 B 型主动脉夹层可以进行药物治疗。从那时起,急性 A 型主动脉夹层(ATAAD)的诊断工具和治疗方法已经发生了重大变化。本文评估了自 50 年前主动脉夹层分类建立以来斯坦福大学 ATAAD 修复的历史变化。回顾了近端和远端主动脉的手术方法、脑灌注方法和插管策略。还对 1967 年至 2019 年 12 月在斯坦福大学接受 ATAAD 修复的患者进行了额外的分析,以进一步说明斯坦福大学在 ATAAD 治疗方面的经验。随着技术复杂性的增加,术后生存率继续提高。需要进一步研究来确定与本研究中观察到的结果改善相关的因素。

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