• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Ultraviolet B induces proteolytic cleavage of the pyroptosis inducer gasdermin E in keratinocytes.

作者信息

Chen Yujie, Xiao Ta, Xu Song, Gu Heng, Li Min, Chen Xu

机构信息

Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.

Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.

出版信息

J Dermatol Sci. 2020 Nov;100(2):160-163. doi: 10.1016/j.jdermsci.2020.08.014. Epub 2020 Sep 9.

DOI:10.1016/j.jdermsci.2020.08.014
PMID:33004249
Abstract
摘要

相似文献

1
Ultraviolet B induces proteolytic cleavage of the pyroptosis inducer gasdermin E in keratinocytes.紫外线B诱导角质形成细胞中焦亡诱导因子gasdermin E的蛋白水解切割。
J Dermatol Sci. 2020 Nov;100(2):160-163. doi: 10.1016/j.jdermsci.2020.08.014. Epub 2020 Sep 9.
2
Caspase-1 initiates apoptosis in the absence of gasdermin D.半胱氨酸天冬氨酸蛋白酶-1 在没有天冬氨酸半胱氨酸酶 D 的情况下启动细胞凋亡。
Nat Commun. 2019 May 7;10(1):2091. doi: 10.1038/s41467-019-09753-2.
3
Lipidome of narrow-band ultraviolet B irradiated keratinocytes shows apoptotic hallmarks.窄带紫外线 B 辐射角朊细胞的脂质组显示凋亡特征。
Exp Dermatol. 2010 Aug;19(8):e103-10. doi: 10.1111/j.1600-0625.2009.01000.x.
4
Gasdermin C is induced by ultraviolet light and contributes to MMP-1 expression via activation of ERK and JNK pathways.Gasdermin C 由紫外线诱导产生,并通过激活 ERK 和 JNK 通路促进 MMP-1 的表达。
J Dermatol Sci. 2018 May;90(2):180-189. doi: 10.1016/j.jdermsci.2018.01.015. Epub 2018 Feb 1.
5
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.化疗药物通过半胱天冬酶-3 对 gasdermin 的切割诱导细胞焦亡。
Nature. 2017 Jul 6;547(7661):99-103. doi: 10.1038/nature22393. Epub 2017 May 1.
6
Nrf2-mediated protection against UVA radiation in human skin keratinocytes.Nrf2 介导的人皮肤角质细胞对抗 UVA 辐射的保护作用。
Biosci Trends. 2011;5(1):23-9. doi: 10.5582/bst.2011.v5.1.23.
7
Caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes.半胱天冬酶-1的活性是紫外线B诱导人角质形成细胞凋亡所必需的。
J Invest Dermatol. 2015 May;135(5):1395-1404. doi: 10.1038/jid.2014.551. Epub 2015 Jan 6.
8
Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance.人类HaCaT角质形成细胞长期接受紫外线A照射会诱导其发生恶性转化,并伴有获得性凋亡抗性。
Oncogene. 2006 Jun 22;25(26):3680-8. doi: 10.1038/sj.onc.1209384. Epub 2006 May 8.
9
Role of p53 in UVB-induced apoptosis in human HaCaT keratinocytes.p53在紫外线B诱导的人HaCaT角质形成细胞凋亡中的作用。
J Invest Dermatol. 1997 Dec;109(6):722-7. doi: 10.1111/1523-1747.ep12340708.
10
Pollen and UV-B radiation strongly affect the inflammasome response in human primary keratinocytes.花粉和紫外线B辐射强烈影响人原代角质形成细胞中的炎性小体反应。
Exp Dermatol. 2016 Dec;25(12):991-993. doi: 10.1111/exd.13120. Epub 2016 Nov 3.

引用本文的文献

1
The gasdermins: a pore-forming protein family expressed in the epidermis.Gasdermin家族:一类在表皮中表达的成孔蛋白家族。
Front Immunol. 2023 Sep 12;14:1254150. doi: 10.3389/fimmu.2023.1254150. eCollection 2023.
2
Gasdermin E (GSDME)-A New Potential Marker of Psoriasis and Its Metabolic Complications: The First Combined Study on Human Serum, Urine and Tissue.Gasdermin E (GSDME)-一种新的银屑病及其代谢并发症的潜在标志物:血清、尿液和组织的首次联合研究。
Cells. 2023 Aug 26;12(17):2149. doi: 10.3390/cells12172149.
3
Gasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis.
Gasdermin D 介导的角质形成细胞细胞焦亡是银屑病发病机制中的关键步骤。
Cell Death Dis. 2023 Sep 7;14(9):595. doi: 10.1038/s41419-023-06094-3.
4
Aberrant inflammasome activation as a driving force of human autoimmune skin disease.异常的炎性体激活作为人类自身免疫性皮肤病的驱动因素。
Front Immunol. 2023 May 30;14:1190388. doi: 10.3389/fimmu.2023.1190388. eCollection 2023.
5
The gasdermin protein family: emerging roles in gastrointestinal health and disease.gasdermin 蛋白家族:在胃肠道健康和疾病中的新作用。
Nat Rev Gastroenterol Hepatol. 2023 Jun;20(6):366-387. doi: 10.1038/s41575-023-00743-w. Epub 2023 Feb 13.
6
GSDME deficiency leads to the aggravation of UVB-induced skin inflammation through enhancing recruitment and activation of neutrophils.GSDME 缺失通过增强中性粒细胞的募集和激活导致 UVB 诱导的皮肤炎症加重。
Cell Death Dis. 2022 Oct 1;13(10):841. doi: 10.1038/s41419-022-05276-9.
7
Pyroptosis and Its Role in Autoimmune Disease: A Potential Therapeutic Target.细胞焦亡及其在自身免疫性疾病中的作用:一个潜在的治疗靶点。
Front Immunol. 2022 May 25;13:841732. doi: 10.3389/fimmu.2022.841732. eCollection 2022.